Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
2002-10-9
pubmed:abstractText
In studies assessing sustained attention in humans, performance is often characterised by a decline in function over time. This response pattern, termed the vigilance decrement, is sensitive to manipulations affecting task difficulty, and to reversal with psychostimulant drugs. A valid test of attention in non-human species requires both comparable characteristics of performance, and sensitivity to similar psychoactive drugs. The five-choice serial reaction time task (5-CSRTT) has been described as a test of sustained attention in the rat, however, studies describing vigilance decrements and performance effects of psychostimulants in this task are scarce.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
0033-3158
pubmed:author
pubmed:issnType
Print
pubmed:volume
164
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
33-41
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
2002
pubmed:articleTitle
Assessing a vigilance decrement in aged rats: effects of pre-feeding, task manipulation, and psychostimulants.
pubmed:affiliation
PRBN-B, F. Hoffmann-La Roche AG, 4070 Basel, Switzerland. agrottick@arenapharm.com
pubmed:publicationType
Journal Article, Comparative Study