|
rdf:type |
|
|
lifeskim:mentions |
umls-concept:C0002092,
umls-concept:C0011306,
umls-concept:C0114967,
umls-concept:C0123759,
umls-concept:C0205164,
umls-concept:C0242568,
umls-concept:C0348080,
umls-concept:C0441655,
umls-concept:C0441889,
umls-concept:C0597304,
umls-concept:C0998367
|
|
pubmed:issue |
10
|
|
pubmed:dateCreated |
2002-10-9
|
|
pubmed:abstractText |
The proteolytic activity of the house dust mite allergen Der p 1 has recently been shown to bias Th cell subset development in favour of Th2. Apart from its direct effect on T cells, it is conceivable that the proteolytic activity of Der p 1 may induce the generation of dendritic cells (DCs) that favour a Th2 response.
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Oct
|
|
pubmed:issn |
0954-7894
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:volume |
32
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
1468-75
|
|
pubmed:dateRevised |
2011-11-17
|
|
pubmed:meshHeading |
pubmed-meshheading:12372127-Animals,
pubmed-meshheading:12372127-Antigens, CD40,
pubmed-meshheading:12372127-Antigens, Dermatophagoides,
pubmed-meshheading:12372127-Arthropod Proteins,
pubmed-meshheading:12372127-Biological Markers,
pubmed-meshheading:12372127-Cells, Cultured,
pubmed-meshheading:12372127-Cysteine Endopeptidases,
pubmed-meshheading:12372127-Dendritic Cells,
pubmed-meshheading:12372127-Humans,
pubmed-meshheading:12372127-Hypersensitivity, Immediate,
pubmed-meshheading:12372127-Immunophenotyping,
pubmed-meshheading:12372127-Interleukin-12,
pubmed-meshheading:12372127-Lipopolysaccharides,
pubmed-meshheading:12372127-Th2 Cells
|
|
pubmed:year |
2002
|
|
pubmed:articleTitle |
The proteolytic activity of the major dust mite allergen Der p 1 conditions dendritic cells to produce less interleukin-12: allergen-induced Th2 bias determined at the dendritic cell level.
|
|
pubmed:affiliation |
Division of Molecular & Clinical Immunology, Faculty of Medicine and Health Sciences, University of Nottingham, Queen's Medical Centre, Nottingham, UK.
|
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|
