Linked Life Data

12370996

Source:http://linkedlifedata.com/resource/pubmed/id/12370996

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
2002-10-9
pubmed:abstractText
Although the radiographic appearance of pulmonary MAC infection in the immunocompetent host can be varied, there are several generalizations that can be made. The classic radiographic appearance is indistinguishable from that of pulmonary tuberculosis. The classic form is seen most commonly in males and is typically associated with other predisposing diseases, especially chronic obstructive pulmonary disease. Most patients have upper lobe disease with associated pleural thickening. Widespread disease is common, as is cavitation. Pleural effusions and adenopathy are uncommon. The Lady Windermere syndrome is a special form of pulmonary MAC seen primarily in middle-aged and elderly women. The radiographic findings are bronchiectasis and small nodules, predominately located within the middle lobe and lingula. The combination of bronchiectasis involving exclusively, or primarily, the right middle lobe and lingula is highly suggestive of pulmonary MAC, even in the face of negative sputum cultures. Pulmonary infection with MAC in the immunocompromised patient generally reflects a widespread systemic disease. As such, the radiographic appearance is highly variable. Diffuse pulmonary opacities and adenopathy are common features. Plain radiographs are frequently normal despite active pulmonary infection. Regardless of the clinical situation, pulmonary MAC infection is often omitted from the radiographic differential even when the appearance is characteristic. In general, when pulmonary abnormalities are identified that are consistent with a granulomatous infection, pulmonary MAC needs to be considered along with tuberculosis and fungal infection. Especially with pulmonary MAC, radiographic stability over several years does not exclude active disease. The radiographic appearance may be suggestive of the diagnosis of pulmonary MAC, but correlation with the clinical and microbiological data is necessary to confirm the diagnosis.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
0272-5231
pubmed:author
pubmed:issnType
Print
pubmed:volume
23
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
603-12
pubmed:dateRevised
2005-11-16
pubmed:meshHeading
pubmed:year
2002
pubmed:articleTitle
Radiology of pulmonary Mycobacterium avium-intracellulare complex.
pubmed:affiliation
Department of Radiology, Mail Code 8756, University of California-San Diego Medical Center, 200 West Arbor Drive, San Diego, CA 92103-8756, USA. dlevin@ucsd.edu
pubmed:publicationType
Journal Article, Review