Source:http://linkedlifedata.com/resource/pubmed/id/12368142
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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
5
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| pubmed:dateCreated |
2002-10-7
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| pubmed:abstractText |
The interest of serum protein immunofixation in myeloma and Waldenstr m's macroglobulinemia is widely known. It is not so well defined in other malignant hemopathies. The purpose of this study was to determine immunofixation abnormalities in malignant hemopathies other than multiple myeloma and Waldenstr m's macroglobulinemia. We selected serum immunofixations of 61 patients affected by malignant hemopathies and 53 patients affected by other pathologies susceptible to give immunofixation's alterations. We showed that the frequency of immunofixation abnormalities was more important in patients affected by malignant hemopathies than in patients affected by other pathologies (70.5% vs 35.8%). A high frequency of monoclonal immunoglobulins was found in patients with lymphoma (53.3%) and oligoclonal immunoglobulins in other hemopathies (48.2%). No significant difference of the frequency of the monoclonal immunoglobulin isotypes was found. In summary, this retrospective study demonstrates a high frequency of immunofixation abnormalities in malignant hemopathies other than multiple myeloma and Waldenstr m's macroglobulinemia and different immunofixation characteristics between lymphomas and other hemopathies.
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| pubmed:language |
fre
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
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| pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Antibodies, Monoclonal,
http://linkedlifedata.com/resource/pubmed/chemical/Immunoglobulin G,
http://linkedlifedata.com/resource/pubmed/chemical/Immunoglobulin Isotypes,
http://linkedlifedata.com/resource/pubmed/chemical/Immunoglobulin M,
http://linkedlifedata.com/resource/pubmed/chemical/Immunoglobulins,
http://linkedlifedata.com/resource/pubmed/chemical/Oligoclonal Bands
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| pubmed:status |
MEDLINE
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| pubmed:issn |
0003-3898
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| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
60
|
| pubmed:owner |
NLM
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| pubmed:authorsComplete |
Y
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| pubmed:pagination |
565-70
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| pubmed:dateRevised |
2007-11-15
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| pubmed:meshHeading |
pubmed-meshheading:12368142-Aged,
pubmed-meshheading:12368142-Antibodies, Monoclonal,
pubmed-meshheading:12368142-Blood Protein Electrophoresis,
pubmed-meshheading:12368142-Case-Control Studies,
pubmed-meshheading:12368142-Electrophoresis, Agar Gel,
pubmed-meshheading:12368142-Female,
pubmed-meshheading:12368142-Humans,
pubmed-meshheading:12368142-Immunoblotting,
pubmed-meshheading:12368142-Immunoelectrophoresis,
pubmed-meshheading:12368142-Immunoglobulin G,
pubmed-meshheading:12368142-Immunoglobulin Isotypes,
pubmed-meshheading:12368142-Immunoglobulin M,
pubmed-meshheading:12368142-Immunoglobulins,
pubmed-meshheading:12368142-Leukemia, Lymphocytic, Chronic, B-Cell,
pubmed-meshheading:12368142-Leukemia, Myelogenous, Chronic, BCR-ABL Positive,
pubmed-meshheading:12368142-Lymphoma,
pubmed-meshheading:12368142-Male,
pubmed-meshheading:12368142-Middle Aged,
pubmed-meshheading:12368142-Multiple Myeloma,
pubmed-meshheading:12368142-Oligoclonal Bands,
pubmed-meshheading:12368142-Waldenstrom Macroglobulinemia
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| pubmed:articleTitle |
[Serum protein immunofixation in malignant hemopathies other than multiple myeloma and Waldenstrom's macroglobulinemia].
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| pubmed:affiliation |
Laboratoire central de biochimie, Hôpital Robert-Debré, Centre hospitalier universitaire, avenue du Général-Koenig, 51092 Reims cedex, France.
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| pubmed:publicationType |
Journal Article,
English Abstract,
Validation Studies
|