Linked Life Data

12364530

Source:http://linkedlifedata.com/resource/pubmed/id/12364530

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
2002-10-4
pubmed:abstractText
Previous studies of visual processing in humans using event-related potentials (ERPs) have demonstrated that task-related modulations of an early component called the "N1" wave (140-200 ms) reflect the operation of a voluntary discrimination process. Specifically, this component is larger in tasks requiring target discrimination than in tasks requiring simple detection. The present study was designed to localize this discriminative process in both time and space by means of combined magnetoencephalographic (MEG) and ERP recordings. Discriminative processing led to differential ERP and MEG activity beginning within 150 ms of stimulus onset. Source localization of the combined ERP/MEG data was performed using anatomical constraints from structural magnetic resonance images. These analyses revealed highly reliable and focused activity in regions of inferior occipital-temporal cortex. These findings indicate that the earliest measurable correlates of discriminative operations in the visual system appear as neural activity in circumscribed regions of the ventral processing stream.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
0022-3077
pubmed:author
pubmed:issnType
Print
pubmed:volume
88
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
2088-95
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
2002
pubmed:articleTitle
Localizing visual discrimination processes in time and space.
pubmed:affiliation
Department of Neurology II, Otto-von-Guericke University, D-39120 Magdeburg, Germany. jens-max.hopf@medizin.uni-magdeburg.de
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S., Research Support, U.S. Gov't, Non-P.H.S., Research Support, Non-U.S. Gov't