Source:http://linkedlifedata.com/resource/pubmed/id/12362423
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
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pubmed:dateCreated |
2002-10-3
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pubmed:abstractText |
We initiated a randomized, double-blinded, placebo-controlled trial of intravenous immunoglobulin (IVIG) treatment in myasthenia gravis (MG). Patients received IVIG 2 gm/kg at induction and 1 gm/kg after 3 weeks vs. 5% albumin placebo. The primary efficacy measurement was the change in the quantitative MG Score (QMG) at day 42. Fifteen patients were enrolled (6 to IVIG; 9 to placebo) before the study was terminated because of insufficient IVIG inventories. At day 42, there was no significant difference in primary or secondary outcome measurements between the two groups. In a subsequent 6-week open-label study of IVIG, positive trends were observed.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
0148-639X
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pubmed:author |
pubmed-author:AmatoAnthony AAA,
pubmed-author:BarohnRichard JRJ,
pubmed-author:BryanWilson WWW,
pubmed-author:DayJohn WJW,
pubmed-author:FosterBarbara MBM,
pubmed-author:FreimerMiriam LML,
pubmed-author:JacksonCarlayne ECE,
pubmed-author:KisselJohn TJT,
pubmed-author:Myasthenia Gravis-IVIG Study Group,
pubmed-author:NationsSharon PSP,
pubmed-author:ParryGareth JGJ,
pubmed-author:ThorntonCharles ACA,
pubmed-author:WolfeGil IGI
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pubmed:copyrightInfo |
Copyright 2002 Wiley Periodicals, Inc. Muscle Nerve 26: 549-552, 2002
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pubmed:issnType |
Print
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pubmed:volume |
26
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
549-52
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:12362423-Adult,
pubmed-meshheading:12362423-Double-Blind Method,
pubmed-meshheading:12362423-Female,
pubmed-meshheading:12362423-Humans,
pubmed-meshheading:12362423-Immunization, Passive,
pubmed-meshheading:12362423-Injections, Intravenous,
pubmed-meshheading:12362423-Male,
pubmed-meshheading:12362423-Middle Aged,
pubmed-meshheading:12362423-Myasthenia Gravis,
pubmed-meshheading:12362423-Treatment Outcome
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pubmed:year |
2002
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pubmed:articleTitle |
Randomized, controlled trial of intravenous immunoglobulin in myasthenia gravis.
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pubmed:affiliation |
Department of Neurology, University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd., Dallas, Texas 75390-8897,USA. gil.wolfe@utsouthwestern.edu
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pubmed:publicationType |
Journal Article,
Clinical Trial,
Randomized Controlled Trial
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