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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
5
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pubmed:dateCreated |
2002-10-3
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pubmed:abstractText |
Investigators have noted that primary open-angle glaucoma (POAG) in West Africa has an earlier age of onset and appears to be more clinically severe than in the United States and Europe. Primary open-angle glaucoma patients with mutations in myocilin have a similar phenotype. Therefore, we investigated the role of mutations in myocilin in patients with POAG in a West African population.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
1057-0829
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
11
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
416-20
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pubmed:dateRevised |
2006-11-3
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pubmed:meshHeading |
pubmed-meshheading:12362081-Adult,
pubmed-meshheading:12362081-Aged,
pubmed-meshheading:12362081-Codon,
pubmed-meshheading:12362081-Cytoskeletal Proteins,
pubmed-meshheading:12362081-DNA Mutational Analysis,
pubmed-meshheading:12362081-Exons,
pubmed-meshheading:12362081-Eye Proteins,
pubmed-meshheading:12362081-Female,
pubmed-meshheading:12362081-Ghana,
pubmed-meshheading:12362081-Glaucoma, Open-Angle,
pubmed-meshheading:12362081-Glycoproteins,
pubmed-meshheading:12362081-Humans,
pubmed-meshheading:12362081-Intraocular Pressure,
pubmed-meshheading:12362081-Male,
pubmed-meshheading:12362081-Middle Aged,
pubmed-meshheading:12362081-Mutation, Missense,
pubmed-meshheading:12362081-Point Mutation,
pubmed-meshheading:12362081-Polymerase Chain Reaction,
pubmed-meshheading:12362081-Polymorphism, Genetic,
pubmed-meshheading:12362081-Prevalence
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pubmed:year |
2002
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pubmed:articleTitle |
Prevalence of myocilin mutations in adults with primary open-angle glaucoma in Ghana, West Africa.
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pubmed:affiliation |
Department of Ophthalmology, Duke University Medical Center, Durham, North Carolina 27712, USA. Chall001@mc.duke.edu
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pubmed:publicationType |
Journal Article
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