| pubmed-article:12360560 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:12360560 | lifeskim:mentions | umls-concept:C0034380 | lld:lifeskim |
| pubmed-article:12360560 | lifeskim:mentions | umls-concept:C0085292 | lld:lifeskim |
| pubmed-article:12360560 | pubmed:issue | 5 | lld:pubmed |
| pubmed-article:12360560 | pubmed:dateCreated | 2002-10-2 | lld:pubmed |
| pubmed-article:12360560 | pubmed:abstractText | Stiff person syndrome (SPS) is a rare, chronic disorder characterized by painful spasm and stiffness. We investigated the quality of life (QoL) in SPS patients, and identified factors associated with impairment in patients' QoL. Twenty-four SPS patients (10 men, 14 women; mean age +/- S.D., 52.6 +/- 9.5 years) completed the medical outcomes study Short Form health survey (SF-36), the Beck Depression Inventory (BDI), and a questionnaire asking for sociodemographic and clinical details. Extent of the disease was assessed using a distribution of stiffness score. SPS patients showed markedly reduced mean scores for all dimensions of the SF-36 when compared to norms from the general population of the United Kingdom. QoL scores showed a strong correlation with the extent of the disease. Depression was a common finding; 14 of 24 patients had depressive symptoms as evidenced by the BDI. There was a significant and strong correlation between the BDI score and several SF-36 subscores. This is the first study to address QoL in patients with SPS. We have shown that SPS has a significant impact on patients' reported QoL. The association between depression and QoL highlights the importance of recognizing and treating depression in SPS. | lld:pubmed |
| pubmed-article:12360560 | pubmed:language | eng | lld:pubmed |
| pubmed-article:12360560 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12360560 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:12360560 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:12360560 | pubmed:month | Sep | lld:pubmed |
| pubmed-article:12360560 | pubmed:issn | 0885-3185 | lld:pubmed |
| pubmed-article:12360560 | pubmed:author | pubmed-author:GerschlagerWi... | lld:pubmed |
| pubmed-article:12360560 | pubmed:author | pubmed-author:BrownPeterP | lld:pubmed |
| pubmed-article:12360560 | pubmed:author | pubmed-author:SchragAnetteA | lld:pubmed |
| pubmed-article:12360560 | pubmed:copyrightInfo | Copyright 2002 Movement Disorder Society | lld:pubmed |
| pubmed-article:12360560 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:12360560 | pubmed:volume | 17 | lld:pubmed |
| pubmed-article:12360560 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:12360560 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:12360560 | pubmed:pagination | 1064-7 | lld:pubmed |
| pubmed-article:12360560 | pubmed:dateRevised | 2004-11-17 | lld:pubmed |
| pubmed-article:12360560 | pubmed:meshHeading | pubmed-meshheading:12360560... | lld:pubmed |
| pubmed-article:12360560 | pubmed:meshHeading | pubmed-meshheading:12360560... | lld:pubmed |
| pubmed-article:12360560 | pubmed:meshHeading | pubmed-meshheading:12360560... | lld:pubmed |
| pubmed-article:12360560 | pubmed:meshHeading | pubmed-meshheading:12360560... | lld:pubmed |
| pubmed-article:12360560 | pubmed:meshHeading | pubmed-meshheading:12360560... | lld:pubmed |
| pubmed-article:12360560 | pubmed:meshHeading | pubmed-meshheading:12360560... | lld:pubmed |
| pubmed-article:12360560 | pubmed:meshHeading | pubmed-meshheading:12360560... | lld:pubmed |
| pubmed-article:12360560 | pubmed:meshHeading | pubmed-meshheading:12360560... | lld:pubmed |
| pubmed-article:12360560 | pubmed:meshHeading | pubmed-meshheading:12360560... | lld:pubmed |
| pubmed-article:12360560 | pubmed:meshHeading | pubmed-meshheading:12360560... | lld:pubmed |
| pubmed-article:12360560 | pubmed:meshHeading | pubmed-meshheading:12360560... | lld:pubmed |
| pubmed-article:12360560 | pubmed:year | 2002 | lld:pubmed |
| pubmed-article:12360560 | pubmed:articleTitle | Quality of life in stiff-person syndrome. | lld:pubmed |
| pubmed-article:12360560 | pubmed:affiliation | Sobell Department of Motor Neurosciences and Movement Disorders, Institute of Neurology, Queen Square, London, United Kingdom. willibald.gerschlager@univie.ac.uk | lld:pubmed |
| pubmed-article:12360560 | pubmed:publicationType | Journal Article | lld:pubmed |
