Source:http://linkedlifedata.com/resource/pubmed/id/12360560
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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
5
|
| pubmed:dateCreated |
2002-10-2
|
| pubmed:abstractText |
Stiff person syndrome (SPS) is a rare, chronic disorder characterized by painful spasm and stiffness. We investigated the quality of life (QoL) in SPS patients, and identified factors associated with impairment in patients' QoL. Twenty-four SPS patients (10 men, 14 women; mean age +/- S.D., 52.6 +/- 9.5 years) completed the medical outcomes study Short Form health survey (SF-36), the Beck Depression Inventory (BDI), and a questionnaire asking for sociodemographic and clinical details. Extent of the disease was assessed using a distribution of stiffness score. SPS patients showed markedly reduced mean scores for all dimensions of the SF-36 when compared to norms from the general population of the United Kingdom. QoL scores showed a strong correlation with the extent of the disease. Depression was a common finding; 14 of 24 patients had depressive symptoms as evidenced by the BDI. There was a significant and strong correlation between the BDI score and several SF-36 subscores. This is the first study to address QoL in patients with SPS. We have shown that SPS has a significant impact on patients' reported QoL. The association between depression and QoL highlights the importance of recognizing and treating depression in SPS.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:status |
MEDLINE
|
| pubmed:month |
Sep
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| pubmed:issn |
0885-3185
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| pubmed:author | |
| pubmed:copyrightInfo |
Copyright 2002 Movement Disorder Society
|
| pubmed:issnType |
Print
|
| pubmed:volume |
17
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| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
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| pubmed:pagination |
1064-7
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| pubmed:dateRevised |
2004-11-17
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| pubmed:meshHeading |
pubmed-meshheading:12360560-Chronic Disease,
pubmed-meshheading:12360560-Cost of Illness,
pubmed-meshheading:12360560-Depressive Disorder, Major,
pubmed-meshheading:12360560-Female,
pubmed-meshheading:12360560-Health Status,
pubmed-meshheading:12360560-Humans,
pubmed-meshheading:12360560-Male,
pubmed-meshheading:12360560-Middle Aged,
pubmed-meshheading:12360560-Quality of Life,
pubmed-meshheading:12360560-Severity of Illness Index,
pubmed-meshheading:12360560-Stiff-Person Syndrome
|
| pubmed:year |
2002
|
| pubmed:articleTitle |
Quality of life in stiff-person syndrome.
|
| pubmed:affiliation |
Sobell Department of Motor Neurosciences and Movement Disorders, Institute of Neurology, Queen Square, London, United Kingdom. willibald.gerschlager@univie.ac.uk
|
| pubmed:publicationType |
Journal Article
|