Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
10
pubmed:dateCreated
2002-10-2
pubmed:abstractText
Transitional ER (tER) sites are ER subdomains that are functionally, biochemically and morphologically distinct from the surrounding rough ER. Here we have used confocal video microscopy to study the dynamics of tER sites and Golgi structures in the budding yeast Pichia pastoris. The biogenesis of tER sites is tightly linked to the biogenesis of Golgi, and both compartments can apparently form de novo. tER sites often fuse with one another, but they maintain a consistent average size through shrinkage after fusion and growth after de novo formation. Golgi dynamics are similar, although late Golgi elements often move away from tER sites towards regions of polarized growth. Our results can be explained by assuming that tER sites give rise to Golgi cisternae that continually mature.
pubmed:commentsCorrections
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
1465-7392
pubmed:author
pubmed:issnType
Print
pubmed:volume
4
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
750-6
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed-meshheading:12360285-COP-Coated Vesicles, pubmed-meshheading:12360285-Cell Compartmentation, pubmed-meshheading:12360285-Cell Differentiation, pubmed-meshheading:12360285-Endoplasmic Reticulum, pubmed-meshheading:12360285-Fungal Proteins, pubmed-meshheading:12360285-Golgi Apparatus, pubmed-meshheading:12360285-Green Fluorescent Proteins, pubmed-meshheading:12360285-Guanine Nucleotide Exchange Factors, pubmed-meshheading:12360285-Intracellular Membranes, pubmed-meshheading:12360285-Luminescent Proteins, pubmed-meshheading:12360285-Membrane Proteins, pubmed-meshheading:12360285-Microscopy, Confocal, pubmed-meshheading:12360285-Microscopy, Video, pubmed-meshheading:12360285-Nuclear Envelope, pubmed-meshheading:12360285-Pichia, pubmed-meshheading:12360285-Recombinant Fusion Proteins, pubmed-meshheading:12360285-Time Factors
pubmed:year
2002
pubmed:articleTitle
De novo formation of transitional ER sites and Golgi structures in Pichia pastoris.
pubmed:affiliation
Department of Molecular Genetics and Cell Biology, The University of Chicago, 920 East 58th Street, Chicago, Illinois 60637, USA.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S., Research Support, Non-U.S. Gov't