Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
10
pubmed:dateCreated
2002-10-2
pubmed:abstractText
A limited list of transcription factors are overactive in most human cancer cells, which makes them targets for the development of anticancer drugs. That they are the most direct and hopeful targets for treating cancer is proposed, and this is supported by the fact that there are many more human oncogenes in signalling pathways than there are oncogenic transcription factors. But how could specific transcription-factor activity be inhibited?
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
1474-175X
pubmed:author
pubmed:issnType
Print
pubmed:volume
2
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
740-9
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed-meshheading:12360277-Antineoplastic Agents, pubmed-meshheading:12360277-Apoptosis, pubmed-meshheading:12360277-Cytoplasm, pubmed-meshheading:12360277-Cytoskeletal Proteins, pubmed-meshheading:12360277-Humans, pubmed-meshheading:12360277-Ligands, pubmed-meshheading:12360277-Models, Biological, pubmed-meshheading:12360277-Mutation, pubmed-meshheading:12360277-NF-kappa B, pubmed-meshheading:12360277-Neoplasms, pubmed-meshheading:12360277-Protein Binding, pubmed-meshheading:12360277-Proto-Oncogene Proteins, pubmed-meshheading:12360277-Signal Transduction, pubmed-meshheading:12360277-Trans-Activators, pubmed-meshheading:12360277-Transcription, Genetic, pubmed-meshheading:12360277-Transcription Factors, pubmed-meshheading:12360277-Wnt Proteins, pubmed-meshheading:12360277-Zebrafish Proteins, pubmed-meshheading:12360277-beta Catenin
pubmed:year
2002
pubmed:articleTitle
Transcription factors as targets for cancer therapy.
pubmed:affiliation
Laboratory of Molecular Cell Biology, The Rockefeller University, 1230 York Avenue, New York, NY 10021, USA. darnell@rockefeller.edu
pubmed:publicationType
Journal Article, Review