Source:http://linkedlifedata.com/resource/pubmed/id/12356819
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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
10
|
| pubmed:dateCreated |
2002-10-1
|
| pubmed:abstractText |
The estimated world-wide prevalence of keratoconus is 50 to 230 per 100,000 in the general population. Sporadic keratoconus is the leading cause of corneal transplantation surgery in Western countries. Positive family history has been reported in 6% to 8% of patients. The purpose of this study was to map the disease locus in 20 Finnish families with autosomal dominant keratoconus, each family having two or more affected members and with no other associated genetic disease.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:status |
MEDLINE
|
| pubmed:month |
Oct
|
| pubmed:issn |
0146-0404
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
43
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
3160-4
|
| pubmed:dateRevised |
2010-11-18
|
| pubmed:meshHeading |
pubmed-meshheading:12356819-Adolescent,
pubmed-meshheading:12356819-Adult,
pubmed-meshheading:12356819-Alleles,
pubmed-meshheading:12356819-Chromosome Mapping,
pubmed-meshheading:12356819-Chromosomes, Human, Pair 16,
pubmed-meshheading:12356819-Female,
pubmed-meshheading:12356819-Finland,
pubmed-meshheading:12356819-Genes, Dominant,
pubmed-meshheading:12356819-Genetic Linkage,
pubmed-meshheading:12356819-Humans,
pubmed-meshheading:12356819-Keratoconus,
pubmed-meshheading:12356819-Lod Score,
pubmed-meshheading:12356819-Male,
pubmed-meshheading:12356819-Pedigree
|
| pubmed:year |
2002
|
| pubmed:articleTitle |
A locus for autosomal dominant keratoconus: linkage to 16q22.3-q23.1 in Finnish families.
|
| pubmed:affiliation |
Department of Obstetrics and Gynecology, Helsinki University Central Hospital, Helsinki, Finland.
|
| pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|