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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
6
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pubmed:dateCreated |
2002-9-30
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pubmed:abstractText |
The fragile histidine triad (FHIT) gene, which is frequently lost in many cancers, has been identified as a candidate tumor suppressor gene at chromosome 3p locus 14.2. Human papillomaviruses (HPVs) are the major cause of cervical carcinoma and have been found to be able to integrate its genes into the chromosome 3 fragile site of cultured cells, deleting a piece of DNA which includes the FHIT gene.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
0179-1958
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pubmed:author |
pubmed-author:BastianAndreasA,
pubmed-author:HuangHeH,
pubmed-author:LuoHe-ShengHS,
pubmed-author:MeierJuris JJJ,
pubmed-author:SchmidtWolfgang EWE,
pubmed-author:SchmitzFrankF,
pubmed-author:SchraderHenningH,
pubmed-author:ShunLai-BaoLB,
pubmed-author:YuBao-PingBP,
pubmed-author:YuHong-GangHG,
pubmed-author:YuJie-PingJP
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pubmed:issnType |
Print
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pubmed:volume |
17
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
396-401
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:12355215-Acid Anhydride Hydrolases,
pubmed-meshheading:12355215-Adenocarcinoma,
pubmed-meshheading:12355215-Chromosome Fragile Sites,
pubmed-meshheading:12355215-Chromosome Fragility,
pubmed-meshheading:12355215-Chromosomes, Human, Pair 3,
pubmed-meshheading:12355215-Colorectal Neoplasms,
pubmed-meshheading:12355215-DNA, Neoplasm,
pubmed-meshheading:12355215-DNA, Viral,
pubmed-meshheading:12355215-Female,
pubmed-meshheading:12355215-Gene Deletion,
pubmed-meshheading:12355215-Genes, Tumor Suppressor,
pubmed-meshheading:12355215-Humans,
pubmed-meshheading:12355215-Male,
pubmed-meshheading:12355215-Middle Aged,
pubmed-meshheading:12355215-Neoplasm Proteins,
pubmed-meshheading:12355215-Papillomaviridae,
pubmed-meshheading:12355215-Papillomavirus Infections,
pubmed-meshheading:12355215-Reverse Transcriptase Polymerase Chain Reaction,
pubmed-meshheading:12355215-Sequence Analysis, DNA,
pubmed-meshheading:12355215-Tumor Virus Infections
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pubmed:year |
2002
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pubmed:articleTitle |
Deletion of the FHIT gene in human colorectal cancer is independent of high-risk HPV infection.
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pubmed:affiliation |
Department of Gastroentrerology, Renmin Hospital of Wuhan University, 430060 Wuhan, China. honggang.yu@ruhr-uni-bochum.de
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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