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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
12 Suppl 1
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pubmed:dateCreated |
2002-9-30
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pubmed:abstractText |
Graft coronary arteriopathy (GCA) after heart transplantation is a major factor limiting the long-term survival of the recipients. Human cytomegalovirus (HCMV) infection is a possible cause of this disease which is characterized by diffuse intimal thickening resulting from smooth muscle cell migration and proliferation. It has been reported that HCMV immediate-early (IE) proteins, IE1 and IE2, could play an important role in the development of this disease; however, the precise in vivo role of these proteins in causing GCA has not been clarified.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/IE1 protein, cytomegalovirus,
http://linkedlifedata.com/resource/pubmed/chemical/IE2 protein, Cytomegalovirus,
http://linkedlifedata.com/resource/pubmed/chemical/Immediate-Early Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Membrane Glycoproteins,
http://linkedlifedata.com/resource/pubmed/chemical/Trans-Activators,
http://linkedlifedata.com/resource/pubmed/chemical/UL115 protein, Human herpesvirus 5,
http://linkedlifedata.com/resource/pubmed/chemical/Viral Envelope Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Viral Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/beta-Galactosidase,
http://linkedlifedata.com/resource/pubmed/chemical/glycoprotein H, Cytomegalovirus,
http://linkedlifedata.com/resource/pubmed/chemical/glycoprotein H, Human...,
http://linkedlifedata.com/resource/pubmed/chemical/glycoprotein O, cytomegalovirus
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pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
1524-4539
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:day |
24
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pubmed:volume |
106
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
I158-62
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:12354726-Animals,
pubmed-meshheading:12354726-Coronary Vessels,
pubmed-meshheading:12354726-Cytomegalovirus Infections,
pubmed-meshheading:12354726-Graft Rejection,
pubmed-meshheading:12354726-Heart Transplantation,
pubmed-meshheading:12354726-Humans,
pubmed-meshheading:12354726-Hyperplasia,
pubmed-meshheading:12354726-Immediate-Early Proteins,
pubmed-meshheading:12354726-Kinetics,
pubmed-meshheading:12354726-Male,
pubmed-meshheading:12354726-Membrane Glycoproteins,
pubmed-meshheading:12354726-Rats,
pubmed-meshheading:12354726-Rats, Inbred Lew,
pubmed-meshheading:12354726-Trans-Activators,
pubmed-meshheading:12354726-Transfection,
pubmed-meshheading:12354726-Viral Envelope Proteins,
pubmed-meshheading:12354726-Viral Proteins,
pubmed-meshheading:12354726-beta-Galactosidase
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pubmed:year |
2002
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pubmed:articleTitle |
Human cytomegalovirus immediate-early protein IE2-86, but not IE1-72, causes graft coronary arteriopathy in the transplanted rat heart.
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pubmed:affiliation |
Harefield Heart Science Centre, Imperial College Faculty of Medicine, Middlesex, UK. k.suzuki@ic.ac.uk
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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