| pubmed-article:12351810 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:12351810 | lifeskim:mentions | umls-concept:C0030705 | lld:lifeskim |
| pubmed-article:12351810 | lifeskim:mentions | umls-concept:C0023448 | lld:lifeskim |
| pubmed-article:12351810 | lifeskim:mentions | umls-concept:C0596901 | lld:lifeskim |
| pubmed-article:12351810 | lifeskim:mentions | umls-concept:C2697913 | lld:lifeskim |
| pubmed-article:12351810 | lifeskim:mentions | umls-concept:C0178719 | lld:lifeskim |
| pubmed-article:12351810 | lifeskim:mentions | umls-concept:C0205178 | lld:lifeskim |
| pubmed-article:12351810 | lifeskim:mentions | umls-concept:C1419053 | lld:lifeskim |
| pubmed-article:12351810 | lifeskim:mentions | umls-concept:C0439677 | lld:lifeskim |
| pubmed-article:12351810 | lifeskim:mentions | umls-concept:C0597360 | lld:lifeskim |
| pubmed-article:12351810 | pubmed:issue | 5 | lld:pubmed |
| pubmed-article:12351810 | pubmed:dateCreated | 2002-9-27 | lld:pubmed |
| pubmed-article:12351810 | pubmed:abstractText | Platelet-activating factor (PAF), a phospholipid mediator with a wide range of actions on mature leukocytes, acts through PAF-receptors (PAF-Rs) on the membranes of responsive cells. No results are available concerning the putative presence of PAF-Rs on leukemic blasts. Using multiparameter flow cytometry, we assessed intracellular and membrane PAF-Rs on blast cells of acute myeloid leukemic (AML) and acute lymphoid leukemic (ALL) patients. Membrane PAF-Rs were documented in 7/15 cases of ALL and 0/28 cases of AML. Putative intracellular PAF-Rs were found in blasts of 8/8 ALL and 13/13 AML patients. Vitamin D(3) and dimethyl sulfoxide that induced the expression of PAF-Rs on the membrane of the human promyelocytic leukemia cell line, HL60, failed to induce their expression on the membranes of CD34(+) AML blasts. The lack of membrane PAF-Rs on the membranes of AML blasts confirms that these receptors represent a marker of mature cells and that their membrane induction is a consequence of cell maturation and differentiation. | lld:pubmed |
| pubmed-article:12351810 | pubmed:language | eng | lld:pubmed |
| pubmed-article:12351810 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12351810 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:12351810 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12351810 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12351810 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12351810 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12351810 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12351810 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12351810 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12351810 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12351810 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12351810 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12351810 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:12351810 | pubmed:issn | 1066-5099 | lld:pubmed |
| pubmed-article:12351810 | pubmed:author | pubmed-author:GuglielmiLL | lld:pubmed |
| pubmed-article:12351810 | pubmed:author | pubmed-author:DenizotYY | lld:pubmed |
| pubmed-article:12351810 | pubmed:author | pubmed-author:BordessouleDD | lld:pubmed |
| pubmed-article:12351810 | pubmed:author | pubmed-author:TurlurePP | lld:pubmed |
| pubmed-article:12351810 | pubmed:author | pubmed-author:DonnardMM | lld:pubmed |
| pubmed-article:12351810 | pubmed:author | pubmed-author:PiguetCC | lld:pubmed |
| pubmed-article:12351810 | pubmed:author | pubmed-author:CouraudM JMJ | lld:pubmed |
| pubmed-article:12351810 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:12351810 | pubmed:volume | 20 | lld:pubmed |
| pubmed-article:12351810 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:12351810 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:12351810 | pubmed:pagination | 394-401 | lld:pubmed |
| pubmed-article:12351810 | pubmed:dateRevised | 2007-11-15 | lld:pubmed |
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| pubmed-article:12351810 | pubmed:meshHeading | pubmed-meshheading:12351810... | lld:pubmed |
| pubmed-article:12351810 | pubmed:meshHeading | pubmed-meshheading:12351810... | lld:pubmed |
| pubmed-article:12351810 | pubmed:meshHeading | pubmed-meshheading:12351810... | lld:pubmed |
| pubmed-article:12351810 | pubmed:meshHeading | pubmed-meshheading:12351810... | lld:pubmed |
| pubmed-article:12351810 | pubmed:meshHeading | pubmed-meshheading:12351810... | lld:pubmed |
| pubmed-article:12351810 | pubmed:meshHeading | pubmed-meshheading:12351810... | lld:pubmed |
| pubmed-article:12351810 | pubmed:meshHeading | pubmed-meshheading:12351810... | lld:pubmed |
| pubmed-article:12351810 | pubmed:meshHeading | pubmed-meshheading:12351810... | lld:pubmed |
| pubmed-article:12351810 | pubmed:meshHeading | pubmed-meshheading:12351810... | lld:pubmed |
| pubmed-article:12351810 | pubmed:meshHeading | pubmed-meshheading:12351810... | lld:pubmed |
| pubmed-article:12351810 | pubmed:meshHeading | pubmed-meshheading:12351810... | lld:pubmed |
| pubmed-article:12351810 | pubmed:meshHeading | pubmed-meshheading:12351810... | lld:pubmed |
| pubmed-article:12351810 | pubmed:meshHeading | pubmed-meshheading:12351810... | lld:pubmed |
| pubmed-article:12351810 | pubmed:meshHeading | pubmed-meshheading:12351810... | lld:pubmed |
| pubmed-article:12351810 | pubmed:meshHeading | pubmed-meshheading:12351810... | lld:pubmed |
| pubmed-article:12351810 | pubmed:meshHeading | pubmed-meshheading:12351810... | lld:pubmed |
| pubmed-article:12351810 | pubmed:meshHeading | pubmed-meshheading:12351810... | lld:pubmed |
| pubmed-article:12351810 | pubmed:meshHeading | pubmed-meshheading:12351810... | lld:pubmed |
| pubmed-article:12351810 | pubmed:meshHeading | pubmed-meshheading:12351810... | lld:pubmed |
| pubmed-article:12351810 | pubmed:meshHeading | pubmed-meshheading:12351810... | lld:pubmed |
| pubmed-article:12351810 | pubmed:meshHeading | pubmed-meshheading:12351810... | lld:pubmed |
| pubmed-article:12351810 | pubmed:year | 2002 | lld:pubmed |
| pubmed-article:12351810 | pubmed:articleTitle | Membrane and intracellular platelet-activating factor receptor expression in leukemic blasts of patients with acute myeloid and lymphoid leukemia. | lld:pubmed |
| pubmed-article:12351810 | pubmed:affiliation | UMR CNRS 6101, Service d'Hématologie Clinique, Service de Pédiatrie, CHU Dupuytren, Limoges, France. | lld:pubmed |
| pubmed-article:12351810 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:12351810 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
