Linked Life Data

12351747

Source:http://linkedlifedata.com/resource/pubmed/id/12351747

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
19
pubmed:dateCreated
2002-9-27
pubmed:abstractText
Working memory is known to involve prefrontal cortex and posterior regions of association cortex (e.g., the inferior temporal lobes). Here, we investigate the potential role of primary somatosensory cortex (SI) in a working memory task with tactile stimuli. Subjects were required to compare the frequencies of two vibrations separated by a retention interval of 1500 msec. Their performance was significantly disrupted when we delivered a pulse of transcranial magnetic stimulation (TMS) to the contralateral SI early (300 or 600 msec) in the retention interval. TMS did not affect tactile working memory if delivered to contralateral SI late in the retention interval (at 900 or 1200 msec), nor did TMS affect performance if delivered to the ipsilateral SI at any time point. Primary sensory cortex thus seems to act not only as a center for on-line sensory processing but also as a transient storage site for information that contributes to working memory.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
1529-2401
pubmed:author
pubmed:issnType
Electronic
pubmed:day
1
pubmed:volume
22
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
8720-5
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
2002
pubmed:articleTitle
Transient storage of a tactile memory trace in primary somatosensory cortex.
pubmed:affiliation
Cognitive Neuroscience Sector, International School for Advanced Studies (SISSA), Trieste 34014, Italy. justinh@psych.usyd.edu.au
pubmed:publicationType
Journal Article, Clinical Trial, Research Support, Non-U.S. Gov't