Linked Life Data

12350333

Source:http://linkedlifedata.com/resource/pubmed/id/12350333

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
10
pubmed:dateCreated
2002-9-27
pubmed:abstractText
Recently, the LAP (for 'LRR and PDZ') family of adaptor proteins was described in vertebrates and invertebrates. The proteins are involved in cell polarity and receptor targeting, and they contain both LRR and PDZ domains in the same molecule, a combination that is specifically bilaterian. A search of available genome sequences reveals a limited number of lap genes, which we have classified by phylogenetic analysis. We propose a functional hypothesis for the origin of this protein family in bilaterians, and give a phylogenetic interpretation of their diversity.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
0168-9525
pubmed:author
pubmed:issnType
Print
pubmed:volume
18
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
494-7
pubmed:dateRevised
2006-10-17
pubmed:meshHeading
pubmed:year
2002
pubmed:articleTitle
The LAP family: a phylogenetic point of view.
pubmed:affiliation
U119 INSERM, Molecular Oncology and Institut Paoli-Calmettes, Molecular Pharmacology, 27, Bd Leï Roure, 13009 Marseille, France.
pubmed:publicationType
Journal Article