Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
1976-12-3
pubmed:abstractText
Offspring of rats treated with 2 mg/kg body weight chlorpromazine (CPZ) on Days 5-8 of gestation had lower seizure thresholds than offspring of saline-treated controls at 30, 60, 90, and 120 days of age. The CPZ-treated offspring were also heavier than controls prior to weaning. Further analysis using cross-fostered litters indicated that at least part of the drug effect on seizure thresholds took place before birth, although a postnatal component was also demonstrated. A striking effect of the fostering experience itself on the seizure threshold prevented conclusions about the relative importance of prenatal and postnatal influences.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Nov
pubmed:issn
0012-1630
pubmed:author
pubmed:issnType
Print
pubmed:volume
8
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
519-24
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1975
pubmed:articleTitle
Effects of testing age and fostering experience on seizure susceptibility of rats treated prenatally with chlorpromazine.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, Non-P.H.S.