rdf:type |
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lifeskim:mentions |
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pubmed:issue |
13
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pubmed:dateCreated |
2002-9-26
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pubmed:abstractText |
Recombinant human activated protein C was shown in the Recombinant Human Activated Protein C Worldwide Evaluation in Severe Sepsis (PROWESS) study to reduce mortality among patients with severe sepsis. A post hoc reanalysis by the Food and Drug Administration (FDA) of data from this study suggested that the reduction in mortality was restricted to patients with Acute Physiology and Chronic Health Evaluation (APACHE II) scores of 25 or more.
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
|
pubmed:citationSubset |
AIM
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pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Sep
|
pubmed:issn |
1533-4406
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pubmed:author |
|
pubmed:copyrightInfo |
Copyright 2002 Massachusetts Medical Society
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pubmed:issnType |
Electronic
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pubmed:day |
26
|
pubmed:volume |
347
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
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pubmed:pagination |
993-1000
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:12324556-APACHE,
pubmed-meshheading:12324556-Adult,
pubmed-meshheading:12324556-Aged,
pubmed-meshheading:12324556-Aged, 80 and over,
pubmed-meshheading:12324556-Anti-Inflammatory Agents, Non-Steroidal,
pubmed-meshheading:12324556-Cost-Benefit Analysis,
pubmed-meshheading:12324556-Female,
pubmed-meshheading:12324556-Humans,
pubmed-meshheading:12324556-Male,
pubmed-meshheading:12324556-Middle Aged,
pubmed-meshheading:12324556-Protein C,
pubmed-meshheading:12324556-Quality-Adjusted Life Years,
pubmed-meshheading:12324556-Recombinant Proteins,
pubmed-meshheading:12324556-Risk,
pubmed-meshheading:12324556-Sepsis,
pubmed-meshheading:12324556-Value of Life
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pubmed:year |
2002
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pubmed:articleTitle |
An economic evaluation of activated protein C treatment for severe sepsis.
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pubmed:affiliation |
Department of Medicine, University of Calgary, Calgary, Alberta, Canada. braden.manns@calgaryhealthregion.ca
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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