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rdf:type |
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lifeskim:mentions |
|
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pubmed:issue |
10
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pubmed:dateCreated |
2002-9-24
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pubmed:abstractText |
Azathioprine therapy is discontinued in one-third of patients with inflammatory bowel disease because of toxicity or a lack of clinical response. Patients with thiopurine methyltransferase (TPMT) deficiency are intolerant to azathioprine, whilst carriers are at increased risk of side-effects.
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pubmed:language |
eng
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pubmed:journal |
|
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pubmed:citationSubset |
IM
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pubmed:chemical |
|
|
pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
0269-2813
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pubmed:author |
|
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pubmed:issnType |
Print
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pubmed:volume |
16
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|
pubmed:owner |
NLM
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|
pubmed:authorsComplete |
Y
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pubmed:pagination |
1743-50
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:12269967-Adult,
pubmed-meshheading:12269967-Azathioprine,
pubmed-meshheading:12269967-Biological Markers,
pubmed-meshheading:12269967-Erythrocytes,
pubmed-meshheading:12269967-Female,
pubmed-meshheading:12269967-Genotype,
pubmed-meshheading:12269967-Humans,
pubmed-meshheading:12269967-Immunosuppressive Agents,
pubmed-meshheading:12269967-Inflammatory Bowel Diseases,
pubmed-meshheading:12269967-Leukocyte Count,
pubmed-meshheading:12269967-Logistic Models,
pubmed-meshheading:12269967-Male,
pubmed-meshheading:12269967-Methyltransferases,
pubmed-meshheading:12269967-Middle Aged,
pubmed-meshheading:12269967-Odds Ratio,
pubmed-meshheading:12269967-Retrospective Studies,
pubmed-meshheading:12269967-Treatment Failure
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pubmed:year |
2002
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pubmed:articleTitle |
Thiopurine methyltransferase activity and the use of azathioprine in inflammatory bowel disease.
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pubmed:affiliation |
Department of Public Health Medicine, GKT School of Medicine, London, UK.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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