Linked Life Data

1225988

Source:http://linkedlifedata.com/resource/pubmed/id/1225988

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3-4
pubmed:dateCreated
1976-8-2
pubmed:abstractText
The effects of various doses of 6-hydroxydopamine (6-OHDA) injected into the hypothalamus on DOCA-salt-induced hypertension were studied. The development of hypertension was prevented in the group treated with the highest dose of 6-OHDA, and the onset of hypertension was delayed in a dose-dependent fashion in the groups treated with the lower doses of 6-OHDA. Catecholamine histofluorescence observations showed that the cannula tips placed the drug lateral to the third ventricle. The most prominent change observed was a marked unilateral reduction in the fluorescence of the dopaminergic nerves of the caudate-putamen and in the number of cell bodies in the substantia nigra. These results suggest possible sites of central aminergic control of blood pressure.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0360-4012
pubmed:author
pubmed:issnType
Print
pubmed:volume
1
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
227-34
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1975
pubmed:articleTitle
Central adrenergic neurons in DOCA-salt hypertension.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S.