Linked Life Data

1225708

Source:http://linkedlifedata.com/resource/pubmed/id/1225708

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
1976-8-2
pubmed:abstractText
The effect of undernutrition on the rate of protein synthesis and the development of metabolic compartmentation of glutamate in the brain was investigated by using [U -14 C] leucine as precursor. In the brain of normal rats the incorporation rate of [14C] leucine into protein was at a maximum during the 3rd week after birth, but in the undernourished animal this rate was markedly lower. The biochemical maturation of the brain, followed in terms of the age-dependent increase in the glutamine/glutamate specific radioactivity ratio, was severly retarded in the undernourished animals, mainly as a result of a marked depression in the conversion of leucine carbon into glutamine. However these biochemical effects of undernutrition were reversible: on rehabilitation from Day 21-35 the rate of conversion of leucine carbon, both into proteins and glutamate and glutamine, was restored to normal.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
0012-1630
pubmed:author
pubmed:issnType
Print
pubmed:volume
8
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
453-64
pubmed:dateRevised
2003-11-14
pubmed:meshHeading
pubmed:year
1975
pubmed:articleTitle
Effect of undernutrition on metabolic compartmentation of glutamate and on the incorporation of [14C] leucine into protein in the developing rat brain.
pubmed:publicationType
Journal Article