12243365

Source:http://linkedlifedata.com/resource/pubmed/id/12243365

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0002085, umls-concept:C0022658, umls-concept:C0030705, umls-concept:C0039260, umls-concept:C0052198, umls-concept:C0332307, umls-concept:C0376249
pubmed:issue	4
pubmed:dateCreated	2002-9-23
pubmed:abstractText	Diabetes is one of the major causes of end stage renal failure in Taiwan. Previous studies have indicated that lipid abnormalities might contribute to the development and progression of diabetic nephropathy (DN). Apolipoprotein E (apo E) regulates the metabolism of lipoproteins. Three different apo E alleles (epsilon2, epsilon3 and epsilon4) produce apo E isoproteins, apo E2, apo E3 and apo E4. Thus, the apo E gene polymorphism may be associated with DN.
pubmed:language	eng
pubmed:journal	http://linkedlifedata.com/resource/pubmed/journal/9012268
pubmed:citationSubset	IM
pubmed:chemical	http://linkedlifedata.com/resource/pubmed/chemical/Apolipoproteins A
pubmed:status	MEDLINE
pubmed:issn	1121-8428
pubmed:author	pubmed-author:ChenHung-ChunHC, pubmed-author:HsiehMing-ChiaMC, pubmed-author:LinJiun-NongJN, pubmed-author:LinShiu-RuSR, pubmed-author:ShinShyi-JangSJ, pubmed-author:YangYuan-ChiehYC
pubmed:issnType	Print
pubmed:volume	15
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	368-73
pubmed:dateRevised	2006-11-15
pubmed:meshHeading	pubmed-meshheading:12243365-Adult, pubmed-meshheading:12243365-Age Distribution, pubmed-meshheading:12243365-Aged, pubmed-meshheading:12243365-Alleles, pubmed-meshheading:12243365-Analysis of Variance, pubmed-meshheading:12243365-Apolipoproteins A, pubmed-meshheading:12243365-Case-Control Studies, pubmed-meshheading:12243365-Chi-Square Distribution, pubmed-meshheading:12243365-Cohort Studies, pubmed-meshheading:12243365-Comorbidity, pubmed-meshheading:12243365-Diabetes Mellitus, Type 2, pubmed-meshheading:12243365-Diabetic Nephropathies, pubmed-meshheading:12243365-Female, pubmed-meshheading:12243365-Gene Frequency, pubmed-meshheading:12243365-Heterozygote, pubmed-meshheading:12243365-Humans, pubmed-meshheading:12243365-Male, pubmed-meshheading:12243365-Middle Aged, pubmed-meshheading:12243365-Polymorphism, Genetic, pubmed-meshheading:12243365-Prevalence, pubmed-meshheading:12243365-Probability, pubmed-meshheading:12243365-Prognosis, pubmed-meshheading:12243365-Reference Values, pubmed-meshheading:12243365-Risk Assessment, pubmed-meshheading:12243365-Sex Distribution, pubmed-meshheading:12243365-Taiwan
pubmed:articleTitle	Higher frequency of apolipoprotein E2 allele in type 2 diabetic patients with nephropathy in Taiwan.
pubmed:affiliation	Department of Internal Medicine, Kaohsiung Medical University, Taiwan.
pubmed:publicationType	Journal Article, Comparative Study