Source:http://linkedlifedata.com/resource/pubmed/id/12240993
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
7-8
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pubmed:dateCreated |
2002-9-20
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pubmed:abstractText |
The biotransformation of the phytoanticipin HBOA and its major degradation metabolites 2-hydroxy-N-(2-hydroxyphenyl)acetamide (7) and N-(2-hydroxyphenyl)acetamide (8) by Chaetosphaeria sp., an endophytic fungus isolated from Aphelandra tetragona, was studied. Three new metabolites could be identified as 2-amino-7-hydroxy-3H-phenoxazin-3-one (12), 2-acetylamino-7-hydroxy-3H-phenoxazin-3-one (13) and 7-hydroxy-2-(2-hydroxyacetyl)-amino-3H-phenoxazin-3-one (14). Structure elucidation of 12 and 13 was performed by MS, 1H, 13C NMR and 2D NMR techniques and confirmed by chemical transformation.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
0939-5075
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
57
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
660-5
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pubmed:dateRevised |
2009-11-4
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pubmed:meshHeading |
pubmed-meshheading:12240993-Acanthaceae,
pubmed-meshheading:12240993-Asteraceae,
pubmed-meshheading:12240993-Benzoxazines,
pubmed-meshheading:12240993-Biotransformation,
pubmed-meshheading:12240993-Chromatography, High Pressure Liquid,
pubmed-meshheading:12240993-Hydroxylation,
pubmed-meshheading:12240993-Hypocreales,
pubmed-meshheading:12240993-Magnetic Resonance Spectroscopy,
pubmed-meshheading:12240993-Models, Molecular,
pubmed-meshheading:12240993-Molecular Conformation,
pubmed-meshheading:12240993-Oxazines
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pubmed:articleTitle |
Hydroxylated 2-amino-3H-phenoxazin-3-one derivatives as products of 2-hydroxy-1,4-benzoxazin-3-one (HBOA) biotransformation by Chaetosphaeria sp., an endophytic fungus from Aphelandra tetragona.
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pubmed:affiliation |
Organisch-chemisches Institut der Universität Zürich, Switzerland.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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