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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
|
pubmed:dateCreated |
1976-7-6
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pubmed:abstractText |
A comparative study was performed to assess the sensitivity and specificity of counterimmunoelectrophoresis (CIEP) and radioimmunoassay (RIA) for the detection of hepatitis B surface antigen. The 8,823 sera examined included selected reference panels and sera collected from populations with low, moderate and high rates of chronic antigen carriage. Overall, hepatitis B surface antigen was detected in 265 sera by CIEP and in 376 by RIA. As well as detecting 46.4% additional positives, the RIA test detected all CIEP-positive sera; i.e., there were no false negative results. However, 150 sera (1.8% of the total tested) gave a positive result by RIA which was not repeatable on retesting. The explanation for this phenomenon appeared to lie in inadequate washing of the antibody-coated tubes.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Oct
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pubmed:issn |
0031-3025
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
7
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
285-92
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:1223718-Blood Donors,
pubmed-meshheading:1223718-Carrier State,
pubmed-meshheading:1223718-Child,
pubmed-meshheading:1223718-Counterimmunoelectrophoresis,
pubmed-meshheading:1223718-False Positive Reactions,
pubmed-meshheading:1223718-Female,
pubmed-meshheading:1223718-Hepatitis B,
pubmed-meshheading:1223718-Hepatitis B Antigens,
pubmed-meshheading:1223718-Humans,
pubmed-meshheading:1223718-Mass Screening,
pubmed-meshheading:1223718-Pregnancy,
pubmed-meshheading:1223718-Radioimmunoassay
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pubmed:year |
1975
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pubmed:articleTitle |
The detection of hepatitis B surface antigen by radioimmunoassay.
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pubmed:publicationType |
Journal Article,
Comparative Study
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