Linked Life Data

1223335

Source:http://linkedlifedata.com/resource/pubmed/id/1223335

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
1976-7-6
pubmed:abstractText
Experimental Tyzzer's disease in weanling mice was enhanced by CCl4 treatment made 1 hr after intravenous infection at doses more than 0.5 ml/kg body weight. Such effect of CCl4 was demonstrated also when the drug was given 4 days before but not when given 2 days after infection. Later than 4 days of infection significant difference was seen between CCl4-treated and non-treated groups in body weight loss, production of hepatic lesions and bacterial growth in the liver. In mice infected after CCl4 administration, necrotic foci and intracellular organisms appeared mostly at the intermediate rather than the central zone of hepatic acini, while CCl4 is known to damage selectively the latter. The results suggested that enhanced bacterial growth might depend upon activated and proliferating hepatocytes at the intermediate acinar zone during a restoration process occurring after CCl4 damage at the centrilobular zone.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
0021-5031
pubmed:author
pubmed:issnType
Print
pubmed:volume
45
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
393-402
pubmed:dateRevised
2003-11-14
pubmed:meshHeading
pubmed:year
1975
pubmed:articleTitle
Effect of carbon tetrachloride on experimental Tyzzer's disease of mice.
pubmed:publicationType
Journal Article