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rdf:type |
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lifeskim:mentions |
umls-concept:C0020792,
umls-concept:C0027651,
umls-concept:C0030415,
umls-concept:C0205155,
umls-concept:C1511577,
umls-concept:C1522472,
umls-concept:C1551341,
umls-concept:C1552858,
umls-concept:C1552923,
umls-concept:C1552924,
umls-concept:C1555029,
umls-concept:C1705191
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pubmed:issue |
9
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|
pubmed:dateCreated |
2002-9-16
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pubmed:abstractText |
Overexpression of cyclin D1 mRNA and protein as a result of the chromosomal translocation t(11;14)(q13;q32) is a highly specific molecular marker of mantle cell lymphoma, but cyclin D1 dysregulation can also be found in other B-cell neoplasias. The aim of the study was to develop a precise and reliable tool for quantitation of cyclin D1 mRNA suitable for archival clinical specimens.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
1078-0432
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
8
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
2902-11
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pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:12231535-Chromosomes, Human, Pair 11,
pubmed-meshheading:12231535-Chromosomes, Human, Pair 14,
pubmed-meshheading:12231535-Computer Systems,
pubmed-meshheading:12231535-Cyclin D1,
pubmed-meshheading:12231535-Gene Expression Regulation, Neoplastic,
pubmed-meshheading:12231535-Humans,
pubmed-meshheading:12231535-Leukemia, B-Cell,
pubmed-meshheading:12231535-Leukemia, Hairy Cell,
pubmed-meshheading:12231535-Leukemia, Lymphocytic, Chronic, B-Cell,
pubmed-meshheading:12231535-Lymphoid Tissue,
pubmed-meshheading:12231535-Lymphoma, B-Cell,
pubmed-meshheading:12231535-Lymphoma, B-Cell, Marginal Zone,
pubmed-meshheading:12231535-Lymphoma, Follicular,
pubmed-meshheading:12231535-Lymphoma, Mantle-Cell,
pubmed-meshheading:12231535-Multiple Myeloma,
pubmed-meshheading:12231535-Neoplasm Proteins,
pubmed-meshheading:12231535-Paraffin Embedding,
pubmed-meshheading:12231535-Pseudolymphoma,
pubmed-meshheading:12231535-RNA, Messenger,
pubmed-meshheading:12231535-RNA, Neoplasm,
pubmed-meshheading:12231535-Reverse Transcriptase Polymerase Chain Reaction,
pubmed-meshheading:12231535-Translocation, Genetic
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pubmed:year |
2002
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pubmed:articleTitle |
Identification of cyclin D1 mRNA overexpression in B-cell neoplasias by real-time reverse transcription-PCR of microdissected paraffin sections.
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pubmed:affiliation |
Institute of Pathology, GSF-National Research Centre for Environment and Health, D-85764 Neuherberg, Germany.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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