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rdf:type |
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lifeskim:mentions |
umls-concept:C0004057,
umls-concept:C0019134,
umls-concept:C0030705,
umls-concept:C0034656,
umls-concept:C0205178,
umls-concept:C0205195,
umls-concept:C0206460,
umls-concept:C0247025,
umls-concept:C0332293,
umls-concept:C0702240,
umls-concept:C0948089,
umls-concept:C1705187,
umls-concept:C2603343
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pubmed:issue |
3
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pubmed:dateCreated |
2002-9-13
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pubmed:abstractText |
In comparison with treatment with unfractionated heparin (UFH) and aspirin (ASA), both tirofiban administered with UFH and ASA, and enoxaparin plus ASA have shown superiority in reducing cardiac ischemic events in patients with unstable angina and non-ST-segment elevation myocardial infarction. Replacing UFH with enoxaparin when tirofiban is administered to patients may offer further therapeutic benefit, but could also increase bleeding.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
1097-6744
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pubmed:author |
pubmed-author:ACUTE II Investigators,
pubmed-author:BigonziFrederiqueF,
pubmed-author:BorzakStevenS,
pubmed-author:CohenMarcM,
pubmed-author:DAYG WGW,
pubmed-author:FreyMartin JMJ,
pubmed-author:HarrisKathyK,
pubmed-author:MukherjeeRobinR,
pubmed-author:SenatoreFredF,
pubmed-author:ThérouxPierreP,
pubmed-author:Van MieghemWW,
pubmed-author:WhiteHarvey DHD
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pubmed:issnType |
Electronic
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pubmed:volume |
144
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
470-7
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:12228784-Adult,
pubmed-meshheading:12228784-Aged,
pubmed-meshheading:12228784-Aged, 80 and over,
pubmed-meshheading:12228784-Aspirin,
pubmed-meshheading:12228784-Coronary Disease,
pubmed-meshheading:12228784-Double-Blind Method,
pubmed-meshheading:12228784-Drug Therapy, Combination,
pubmed-meshheading:12228784-Electrocardiography,
pubmed-meshheading:12228784-Enoxaparin,
pubmed-meshheading:12228784-Female,
pubmed-meshheading:12228784-Fibrinolytic Agents,
pubmed-meshheading:12228784-Hemorrhage,
pubmed-meshheading:12228784-Heparin,
pubmed-meshheading:12228784-Humans,
pubmed-meshheading:12228784-Infusions, Intravenous,
pubmed-meshheading:12228784-Male,
pubmed-meshheading:12228784-Middle Aged,
pubmed-meshheading:12228784-Platelet Glycoprotein GPIIb-IIIa Complex,
pubmed-meshheading:12228784-Treatment Outcome,
pubmed-meshheading:12228784-Tyrosine
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pubmed:year |
2002
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pubmed:articleTitle |
Randomized double-blind safety study of enoxaparin versus unfractionated heparin in patients with non-ST-segment elevation acute coronary syndromes treated with tirofiban and aspirin: the ACUTE II study. The Antithrombotic Combination Using Tirofiban and Enoxaparin.
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pubmed:affiliation |
MCP Hahnemann University School of Medicine, Philadelphia, Pa, USA. marc.cohen@tenethealth.com
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pubmed:publicationType |
Journal Article,
Clinical Trial,
Comparative Study,
Randomized Controlled Trial,
Research Support, Non-U.S. Gov't
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