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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
10
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pubmed:dateCreated |
2002-9-13
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pubmed:abstractText |
We report that the archetypal Escherichia coli strain C5 causing neonatal meningitis harbors a pathogenicity island (PAI) designated PAI I(C5) that is similar to the PAI II(J96) of uropathogenic E. coli J96 inserted in the leuX-tRNA gene. PAI-negative C5 mutants had a lower capacity than C5 to induce high-level bacteremia in a neonatal rat model. However, no change in their resistance to the bactericidal effect of serum and their capacity to cross the blood-brain barrier was observed.
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/12228319-10377140,
http://linkedlifedata.com/resource/pubmed/commentcorrection/12228319-10470563,
http://linkedlifedata.com/resource/pubmed/commentcorrection/12228319-10603385,
http://linkedlifedata.com/resource/pubmed/commentcorrection/12228319-10639454,
http://linkedlifedata.com/resource/pubmed/commentcorrection/12228319-10722606,
http://linkedlifedata.com/resource/pubmed/commentcorrection/12228319-10760174,
http://linkedlifedata.com/resource/pubmed/commentcorrection/12228319-10948125,
http://linkedlifedata.com/resource/pubmed/commentcorrection/12228319-11237832,
http://linkedlifedata.com/resource/pubmed/commentcorrection/12228319-11267772,
http://linkedlifedata.com/resource/pubmed/commentcorrection/12228319-11349064,
http://linkedlifedata.com/resource/pubmed/commentcorrection/12228319-1326000,
http://linkedlifedata.com/resource/pubmed/commentcorrection/12228319-1974320,
http://linkedlifedata.com/resource/pubmed/commentcorrection/12228319-2189890,
http://linkedlifedata.com/resource/pubmed/commentcorrection/12228319-2875989,
http://linkedlifedata.com/resource/pubmed/commentcorrection/12228319-2893810,
http://linkedlifedata.com/resource/pubmed/commentcorrection/12228319-326679,
http://linkedlifedata.com/resource/pubmed/commentcorrection/12228319-365760,
http://linkedlifedata.com/resource/pubmed/commentcorrection/12228319-4604810,
http://linkedlifedata.com/resource/pubmed/commentcorrection/12228319-6187683,
http://linkedlifedata.com/resource/pubmed/commentcorrection/12228319-6363394,
http://linkedlifedata.com/resource/pubmed/commentcorrection/12228319-7031483,
http://linkedlifedata.com/resource/pubmed/commentcorrection/12228319-7507897,
http://linkedlifedata.com/resource/pubmed/commentcorrection/12228319-7591087,
http://linkedlifedata.com/resource/pubmed/commentcorrection/12228319-7844075,
http://linkedlifedata.com/resource/pubmed/commentcorrection/12228319-8751923,
http://linkedlifedata.com/resource/pubmed/commentcorrection/12228319-9278503,
http://linkedlifedata.com/resource/pubmed/commentcorrection/12228319-9350773,
http://linkedlifedata.com/resource/pubmed/commentcorrection/12228319-9498443,
http://linkedlifedata.com/resource/pubmed/commentcorrection/12228319-9746614
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
0019-9567
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
70
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
5865-9
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pubmed:dateRevised |
2009-11-18
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pubmed:meshHeading |
pubmed-meshheading:12228319-Animals,
pubmed-meshheading:12228319-Bacteremia,
pubmed-meshheading:12228319-Base Sequence,
pubmed-meshheading:12228319-Blood Bactericidal Activity,
pubmed-meshheading:12228319-DNA, Bacterial,
pubmed-meshheading:12228319-Disease Models, Animal,
pubmed-meshheading:12228319-Escherichia coli,
pubmed-meshheading:12228319-Escherichia coli Infections,
pubmed-meshheading:12228319-Genes, Bacterial,
pubmed-meshheading:12228319-Humans,
pubmed-meshheading:12228319-Infant, Newborn,
pubmed-meshheading:12228319-Meningitis, Escherichia coli,
pubmed-meshheading:12228319-Molecular Sequence Data,
pubmed-meshheading:12228319-Rats,
pubmed-meshheading:12228319-Rats, Sprague-Dawley,
pubmed-meshheading:12228319-Sequence Deletion,
pubmed-meshheading:12228319-Virulence
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pubmed:year |
2002
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pubmed:articleTitle |
A uropathogenicity island contributes to the pathogenicity of Escherichia coli strains that cause neonatal meningitis.
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pubmed:affiliation |
Laboratoire d'Etudes de Génétique Bactérienne dans les Infections de l'Enfant (EA 3105), Université Denis Diderot-Paris 7, Hôpital Robert Debré, 75019 Paris, France.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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