Linked Life Data

12227129

Source:http://linkedlifedata.com/resource/pubmed/id/12227129

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
2002-9-13
pubmed:abstractText
This review is in accordance with the findings of the systematic review of Airey et al [18] with respect to the absence of a differential effect on hypoglycemia between human and animal insulin. For the first time, however, the review compares the relative efficacies of human and animal insulin, which indicates that human insulin was introduced without proof of being superior to animal insulin. Studies have not assessed patient-centered outcomes [41,42], such as patient satisfaction, health-related quality of life, and diabetes-related morbidity. Randomized trials did not report on qualitative assessments of patients' experiences when using different insulin species. Because history tends to repeat itself, we probably will be faced with other "innovations" (e.g., insulin analogs) evaluated in clinical trials tht focus on surrogate outcomes followed by marketing of insulins "proved" to be effective in short-term, underpowered, and badly executed studies.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
0889-8529
pubmed:author
pubmed:issnType
Print
pubmed:volume
31
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
723-49
pubmed:dateRevised
2011-11-17
pubmed:meshHeading
pubmed:year
2002
pubmed:articleTitle
Human versus animal insulin in people with diabetes mellitus. A systematic review.
pubmed:affiliation
Cochrane Metabolic and Endocrine Disorders Review Group, Department of Metabolic Disorders and Nutrition, Heinrich-Heine University, Moorenstrasse 5, D-40225 Düsseldorf, Germany. richterb@uni-duesseldorf.de
pubmed:publicationType
Journal Article, Comparative Study, Review