Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
17
pubmed:dateCreated
2002-9-12
pubmed:abstractText
TOR is a phosphatidylinositol kinase (PIK)-related kinase that controls cell growth and proliferation in response to nutritional cues. We describe a C. elegans TOR homolog (CeTOR) and phenotypes associated with CeTOR deficiency. These phenotypes are compared with the response to starvation and the inactivation of a variety of putative TOR targets.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
0960-9822
pubmed:author
pubmed:issnType
Print
pubmed:day
3
pubmed:volume
12
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1448-61
pubmed:dateRevised
2010-3-23
pubmed:meshHeading
pubmed-meshheading:12225660-Adaptation, Physiological, pubmed-meshheading:12225660-Alleles, pubmed-meshheading:12225660-Animals, pubmed-meshheading:12225660-Atrophy, pubmed-meshheading:12225660-Caenorhabditis elegans, pubmed-meshheading:12225660-Caenorhabditis elegans Proteins, pubmed-meshheading:12225660-Eukaryotic Initiation Factor-2, pubmed-meshheading:12225660-Eukaryotic Initiation Factor-4G, pubmed-meshheading:12225660-Gene Expression Regulation, Developmental, pubmed-meshheading:12225660-Gene Targeting, pubmed-meshheading:12225660-Genes, Lethal, pubmed-meshheading:12225660-Genetic Complementation Test, pubmed-meshheading:12225660-Intestines, pubmed-meshheading:12225660-Larva, pubmed-meshheading:12225660-Phenotype, pubmed-meshheading:12225660-Phosphotransferases (Alcohol Group Acceptor), pubmed-meshheading:12225660-Protein Biosynthesis, pubmed-meshheading:12225660-RNA, Messenger, pubmed-meshheading:12225660-RNA Interference, pubmed-meshheading:12225660-Ribosomal Protein S6 Kinases, 70-kDa, pubmed-meshheading:12225660-Sequence Homology, Amino Acid, pubmed-meshheading:12225660-Sirolimus, pubmed-meshheading:12225660-Species Specificity, pubmed-meshheading:12225660-Starvation
pubmed:year
2002
pubmed:articleTitle
TOR deficiency in C. elegans causes developmental arrest and intestinal atrophy by inhibition of mRNA translation.
pubmed:affiliation
Department of Molecular Biology, Massachusetts General Hospital, Harvard Medical School, Boston 02114, USA.
pubmed:publicationType
Journal Article, Comparative Study, Research Support, U.S. Gov't, P.H.S., Research Support, Non-U.S. Gov't