Linked Life Data

12223258

Source:http://linkedlifedata.com/resource/pubmed/id/12223258

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2-3
pubmed:dateCreated
2002-9-11
pubmed:abstractText
Abnormalities of the ependyma can serve as a marker of early brain insults. The presence of ependymal abnormalities was determined in sections containing ependyma of the temporal horn obtained from the Stanley Neuropathology Consortium: 15 subjects with schizophrenia, 15 with bipolar illness, 15 with major depression and 15 normal controls. There were no significant differences in numbers of subjects with ependymal discontinuities or subventricular rosettes. Subjects with schizophrenia had significantly less nodular gliosis than normal subjects (p=0.02); there was a trend for subjects with depression to have less nodular gliosis than normal subjects (p=0.06). Control subjects had unexpectedly high rates of ependymal abnormalities, indicating that ependymal abnormalities may not be a useful marker of pre- or perinatal events associated with schizophrenia and other psychiatric disorders in adult postmortem tissue.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
0920-9964
pubmed:author
pubmed:issnType
Print
pubmed:day
1
pubmed:volume
57
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
267-71
pubmed:dateRevised
2010-9-2
pubmed:meshHeading
pubmed:year
2002
pubmed:articleTitle
Analysis of ependymal abnormalities in subjects with schizophrenia, bipolar disorder, and depression.
pubmed:affiliation
Department of Psychiatry, CB#7160, University of North Carolina School of Medicine, Chapel Hill, NC 27599-7160, USA. jgilmore@med.unc.edu
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S., Research Support, Non-U.S. Gov't