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pubmed-article:12222878pubmed:abstractTextIt has recently been demonstrated that postnatal neovascularization is not restricted to angiogenesis, but also includes vasculogenesis. During adult vasculogenesis, bone marrow (BM)-derived endothelial progenitor cells (EPCs) are recruited to the systemic circulation in response to certain cytokines and/or tissue ischemia, and incorporate into sites of neovascularization. EPCs have also been investigated as therapeutic agents in a 'supply-side' approach to promoting neovascularization under pathological conditions. This review highlights the discovery of BM-derived EPCs and their therapeutic potential for vascular regeneration.lld:pubmed
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pubmed-article:12222878pubmed:articleTitleBone marrow-derived endothelial progenitor cells for vascular regeneration.lld:pubmed
pubmed-article:12222878pubmed:affiliationDivision of Cardiovascular Research, St Elizabeth's Medical Center of Boston, Brighton, MA 02135-2997, USA.lld:pubmed
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