Source:http://linkedlifedata.com/resource/pubmed/id/12222878
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
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pubmed:dateCreated |
2002-9-11
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pubmed:abstractText |
It has recently been demonstrated that postnatal neovascularization is not restricted to angiogenesis, but also includes vasculogenesis. During adult vasculogenesis, bone marrow (BM)-derived endothelial progenitor cells (EPCs) are recruited to the systemic circulation in response to certain cytokines and/or tissue ischemia, and incorporate into sites of neovascularization. EPCs have also been investigated as therapeutic agents in a 'supply-side' approach to promoting neovascularization under pathological conditions. This review highlights the discovery of BM-derived EPCs and their therapeutic potential for vascular regeneration.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
1464-8431
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
4
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
395-402
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:12222878-Animals,
pubmed-meshheading:12222878-Blood Vessels,
pubmed-meshheading:12222878-Bone Marrow,
pubmed-meshheading:12222878-Gene Therapy,
pubmed-meshheading:12222878-Humans,
pubmed-meshheading:12222878-Kinetics,
pubmed-meshheading:12222878-Mice,
pubmed-meshheading:12222878-Regeneration,
pubmed-meshheading:12222878-Stem Cell Transplantation,
pubmed-meshheading:12222878-Stem Cells
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pubmed:year |
2002
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pubmed:articleTitle |
Bone marrow-derived endothelial progenitor cells for vascular regeneration.
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pubmed:affiliation |
Division of Cardiovascular Research, St Elizabeth's Medical Center of Boston, Brighton, MA 02135-2997, USA.
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pubmed:publicationType |
Journal Article,
Review,
Research Support, Non-U.S. Gov't
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