Linked Life Data

12217190

Source:http://linkedlifedata.com/resource/pubmed/id/12217190

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
7
pubmed:dateCreated
2002-9-9
pubmed:abstractText
Six transfusion-dependent beta-thalassemia major patients were treated with allogeneic peripheral blood stem cell (PBSC) transplant. The donors were HLA identical siblings except one donor who was a father with one-antigen mismatch of HLA-B loci. The donors were mobilized with G-CSF and PBSC was infused without manipulation. Engraftment was documented in all patients. Acute graft versus host disease (GvHD) was present in 4 patients but could be controlled with steroid or/and ATG. One patient died of hepatic veno-occlusive disease (HVOD) and survivors were all transfusion independent (ex-thalassemia). Chronic GvHD occurred in one patient. Allogeneic PBSC transplantation could achieve disease-free survival in beta-thalassemia major patients.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:issn
0888-0018
pubmed:author
pubmed:issnType
Print
pubmed:volume
19
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
453-8
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed:articleTitle
Allogeneic peripheral blood stem cell transplantation in beta-thalassemia.
pubmed:affiliation
Department of Pediatrics, Sun Yat-sen Memorial Hospital, Zhong Shan (Sun Yat-sen) University, Guangzhou, People's Republic of China. infor@gdtc.net
pubmed:publicationType
Journal Article, Case Reports