We recently reported that acute retinal necrosis in humans develops in a setting where delayed hypersensitivity (DH) to the varicella-zoster virus (VZV) antigen was absent, implying that virus-specific DH mitigates against acute retinal necrosis.
Department of Ophthalmology, Hachioji Medical Center, Tokyo Medical University, 1163, Tate-machi, Hachioji-city, Tokyo, 193-8639, Japan. tkezuka@tokyo-med.ac.jp