Source:http://linkedlifedata.com/resource/pubmed/id/12215085
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
9
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pubmed:dateCreated |
2002-9-6
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pubmed:abstractText |
There is increasing support for the hypothesis that gonadal steroids involved in the regulation of the human menstrual cycle modulate gamma-aminobutyric acid (GABA) neuronal function. This study tests the hypothesis that cortical GABA neuronal function, reflected in brain GABA concentrations, fluctuates across the menstrual cycle in healthy women and those with premenstrual dysphoric disorder (PMDD) and that a menstrual cycle phase-dependent abnormality in brain GABA concentrations in women diagnosed as having PMDD would reflect altered central response to circulating gonadal and neuroactive steroids.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
0003-990X
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
59
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
851-8
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:12215085-Adult,
pubmed-meshheading:12215085-Cerebral Cortex,
pubmed-meshheading:12215085-Estradiol,
pubmed-meshheading:12215085-Female,
pubmed-meshheading:12215085-Follicular Phase,
pubmed-meshheading:12215085-Humans,
pubmed-meshheading:12215085-Luteal Phase,
pubmed-meshheading:12215085-Magnetic Resonance Spectroscopy,
pubmed-meshheading:12215085-Menstrual Cycle,
pubmed-meshheading:12215085-Occipital Lobe,
pubmed-meshheading:12215085-Pregnanolone,
pubmed-meshheading:12215085-Premenstrual Syndrome,
pubmed-meshheading:12215085-Progesterone,
pubmed-meshheading:12215085-gamma-Aminobutyric Acid
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pubmed:year |
2002
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pubmed:articleTitle |
Cortical gamma-aminobutyric acid levels across the menstrual cycle in healthy women and those with premenstrual dysphoric disorder: a proton magnetic resonance spectroscopy study.
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pubmed:affiliation |
Yale Behavioral Gynecology Program, Department of Psychiatry, Yale University School of Medicine University Towers, Suite 2H, 100 York St, New Haven, CT 06511, USA. neill.epperson@yale.edu
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, U.S. Gov't, Non-P.H.S.
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