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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
2
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pubmed:dateCreated |
2002-9-5
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pubmed:abstractText |
Although the common 677 C --> T polymorphism of the methylenetetrahydrofolate reductase (MTHFR) gene is implicated in the development of hyperhomocysteinemia, its correlation with venous thromboembolism (VTE) remains controversial. We conducted a meta-analysis of previously published studies to clarify the role of the MTHFR 677 TT homozygous genotype in association with VTE.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:issn |
1424-8832
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pubmed:author |
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pubmed:copyrightInfo |
Copyright 2002 S. Karger AG, Basel
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pubmed:issnType |
Print
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pubmed:volume |
32
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
51-8
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pubmed:dateRevised |
2005-11-17
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pubmed:meshHeading |
pubmed-meshheading:12214149-Adult,
pubmed-meshheading:12214149-Case-Control Studies,
pubmed-meshheading:12214149-Databases, Factual,
pubmed-meshheading:12214149-Female,
pubmed-meshheading:12214149-Gene Frequency,
pubmed-meshheading:12214149-Genetic Predisposition to Disease,
pubmed-meshheading:12214149-Genotype,
pubmed-meshheading:12214149-Homozygote,
pubmed-meshheading:12214149-Humans,
pubmed-meshheading:12214149-Male,
pubmed-meshheading:12214149-Methylenetetrahydrofolate Reductase (NADPH2),
pubmed-meshheading:12214149-Middle Aged,
pubmed-meshheading:12214149-Odds Ratio,
pubmed-meshheading:12214149-Oxidoreductases Acting on CH-NH Group Donors,
pubmed-meshheading:12214149-Polymorphism, Single Nucleotide,
pubmed-meshheading:12214149-Risk,
pubmed-meshheading:12214149-Thromboembolism,
pubmed-meshheading:12214149-Venous Thrombosis
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pubmed:articleTitle |
Common C677T polymorphism of the methylenetetrahydrofolate reductase gene and the risk of venous thromboembolism: meta-analysis of 31 studies.
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pubmed:affiliation |
Department of Medicine, Women's College Campus, Sunnybrook and Women's College Health Sciences Centre, Toronto, Ont., Canada. rayjg@mcmaster.ca
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pubmed:publicationType |
Journal Article,
Meta-Analysis
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