Linked Life Data

12213635

Source:http://linkedlifedata.com/resource/pubmed/id/12213635

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
2002-9-5
pubmed:abstractText
In the present study the presence of choline acetyltransferase (ChAT) immunoreactive cells in the adult retina of Xenopus laevis was demonstrated and their appearance and maturation during development were examined. Two cholinergic amacrine cell types were identified in the retina. They were located in the deepest row of cells in the inner nuclear layer and in the ganglion cell layer, respectively. Cell processes from these cells organized distinct laminae within the inner plexiform layer. ChAT immunoreactivity was first observed at embryonic stage 35 coinciding with the onset of vision and increased rapidly in premetamorphosis as synaptogenesis and growth proceeded. The development of both ChAT cell populations occurred simultaneously and cells that expressed ChAT transiently were not observed. Our results contrast with previous studies that suggested a late involvement of acetylcholine in the retina of Xenopus and support the notion that, like in mammals, this transmitter is involved in early phases of neurogenesis, cell migration, neuronal growth, and synaptogenesis.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
0304-3940
pubmed:author
pubmed:issnType
Print
pubmed:day
13
pubmed:volume
330
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
61-4
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
2002
pubmed:articleTitle
Localization of choline acetyltransferase in the developing and adult retina of Xenopus laevis.
pubmed:affiliation
Department of Cell Biology, Faculty of Biology, University Complutense, 28040 Madrid, Spain.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't