Source:http://linkedlifedata.com/resource/pubmed/id/12212234
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
2002-9-5
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pubmed:abstractText |
Fifty-eight systemic lupus erythematosus (SLE) patients and 59 normal controls of the Han nationality in Hunan province were involved in this study to analyze the correlation between HLA-DR2 group specific amplification in combination with HLA-DRB generic amplification PCR/SSCP technique to detect the sequence variation within exon 2 of HLA-DR2 alleles outside the sequence specific primer matching positions. The results were that HLA-DR2 was strongly correlated with SLE (RR = 2.71, P < 0.01); and HLA-DRB1 * 1501 was the allele correlated with disease (RR = 3.01, Pc < 0.05). In addition, PCR/SSCP showed that there was not any novel sequence variation in exon 2 of HLA-DR2 alleles in the Han nationality in Hunan province.
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pubmed:language |
chi
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
1000-5625
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
28
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pubmed:volume |
25
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
15-7
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:12212234-Alleles,
pubmed-meshheading:12212234-Asian Continental Ancestry Group,
pubmed-meshheading:12212234-China,
pubmed-meshheading:12212234-Ethnic Groups,
pubmed-meshheading:12212234-Exons,
pubmed-meshheading:12212234-HLA-DR2 Antigen,
pubmed-meshheading:12212234-Humans,
pubmed-meshheading:12212234-Lupus Erythematosus, Systemic,
pubmed-meshheading:12212234-Polymerase Chain Reaction,
pubmed-meshheading:12212234-Polymorphism, Genetic,
pubmed-meshheading:12212234-Polymorphism, Single-Stranded Conformational
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pubmed:year |
2000
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pubmed:articleTitle |
[Correlative study on HLA-DR2 allelic polymorphism and systemic lupus erythematosus in the Han nationality in Hunan province].
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pubmed:affiliation |
Immunology Research Laboratory, Hunan Medical University, Changsha 410078.
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pubmed:publicationType |
Journal Article,
English Abstract
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