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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
4
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pubmed:dateCreated |
2002-9-4
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pubmed:abstractText |
There are few reports of positron emission tomography (PET) in juvenile parkinsonism (JP). We report on the results of (18)F-6-fluoro-L-dopa (FD) PET in a 14-year-old patient with JP of 5 years duration associated with atypical features. This is the youngest subject to be investigated to date. There was a severe asymmetric reduction in striatal FD uptake, with a rostrocaudal gradient in the putamen similar to that seen in adult-onset idiopathic parkinsonism. Extensive DNA analysis in this patient did not show mutations in the parkin gene.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
0885-3185
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pubmed:author |
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pubmed:copyrightInfo |
Copyright 2002 Movement Disorder Society
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pubmed:issnType |
Print
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pubmed:volume |
17
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
789-94
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:12210877-Adolescent,
pubmed-meshheading:12210877-Caudate Nucleus,
pubmed-meshheading:12210877-Corpus Striatum,
pubmed-meshheading:12210877-DNA Mutational Analysis,
pubmed-meshheading:12210877-Dihydroxyphenylalanine,
pubmed-meshheading:12210877-Dominance, Cerebral,
pubmed-meshheading:12210877-Gene Expression,
pubmed-meshheading:12210877-Humans,
pubmed-meshheading:12210877-Image Processing, Computer-Assisted,
pubmed-meshheading:12210877-Imaging, Three-Dimensional,
pubmed-meshheading:12210877-Ligases,
pubmed-meshheading:12210877-Male,
pubmed-meshheading:12210877-Neurologic Examination,
pubmed-meshheading:12210877-Parkinsonian Disorders,
pubmed-meshheading:12210877-Putamen,
pubmed-meshheading:12210877-Tomography, Emission-Computed,
pubmed-meshheading:12210877-Ubiquitin-Protein Ligases
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pubmed:year |
2002
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pubmed:articleTitle |
[18F]-Dopa positron emission tomography imaging in early-stage, non-parkin juvenile parkinsonism.
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pubmed:affiliation |
Neurodegenerative Disorders Centre, Vancouver Hospital & Health Sciences Centre, University of British Columbia, Vancouver, British Columbia, Canada.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Case Reports,
Research Support, Non-U.S. Gov't
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