Source:http://linkedlifedata.com/resource/pubmed/id/12206868
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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
5
|
| pubmed:dateCreated |
2002-9-3
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| pubmed:abstractText |
A semi-automated method is described for segmenting the cerebellum from T(1)-weighted 3-dimensional magnetic resonance imaging scans of adult controls and patients. The method relies on prior knowledge involving a user-defined template as a guide to aid the segmentation of the cerebellum. As the gray and white matter intensity distribution in the cerebellum has a complex pattern, texture information that identified the "graininess" was employed to capture the intensity distribution of voxels. The textural information was used to group voxels in a small circular structuring element as belonging to the cerebellum region. The cerebella from scans of 15 of the 20 subjects were segmented both manually and using the semi-automated procedure; the results were strongly correlated (r = 0.985, n = 15, p < 0.0001), and the volumes obtained from the two methods differed by 2.3%. The cerebellar volumes in 10 normal subjects and 10 age- and sex-matched patients with a neuropsychiatric disorder (schizophrenia) did not differ significantly (p = 0.18). The whole cerebellum was segmented in approximately 30 min using the semi-automated procedure. The method described is robust, easy-to-use, fairly fast and gives objective measurements.
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| pubmed:language |
eng
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| pubmed:journal | |
| pubmed:citationSubset |
IM
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| pubmed:status |
MEDLINE
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| pubmed:month |
Jun
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| pubmed:issn |
0730-725X
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| pubmed:author | |
| pubmed:issnType |
Print
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| pubmed:volume |
20
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| pubmed:owner |
NLM
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| pubmed:authorsComplete |
Y
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| pubmed:pagination |
425-9
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| pubmed:dateRevised |
2004-11-17
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| pubmed:meshHeading |
pubmed-meshheading:12206868-Cerebellum,
pubmed-meshheading:12206868-Female,
pubmed-meshheading:12206868-Humans,
pubmed-meshheading:12206868-Image Processing, Computer-Assisted,
pubmed-meshheading:12206868-Imaging, Three-Dimensional,
pubmed-meshheading:12206868-Magnetic Resonance Imaging,
pubmed-meshheading:12206868-Male,
pubmed-meshheading:12206868-Schizophrenia
|
| pubmed:year |
2002
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| pubmed:articleTitle |
Cerebellum segmentation employing texture properties and knowledge based image processing: applied to normal adult controls and patients.
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| pubmed:affiliation |
MRI Unit, MRC Clinical Sciences Centre, Imperial College School of Medicine, Hammersmith Hospital, London W12 0HS, UK. nadeem_2_saeed@gsk.com
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| pubmed:publicationType |
Journal Article
|