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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
8
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pubmed:dateCreated |
2002-8-30
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pubmed:abstractText |
Thymol is a naturally occurring phenol derivative used in anaesthetic practice as a stabilizer and preservative of halothane, usually at a concentration of 0.01%. Although analgesic effects have long been described for thymol and its structural homologue menthol, a molecular basis for these effects is still lacking. We studied the blocking effects of thymol and menthol on voltage-activated sodium currents in vitro as possible molecular target sites.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
0265-0215
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
19
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
571-9
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:12200946-Analgesics,
pubmed-meshheading:12200946-Animals,
pubmed-meshheading:12200946-Anti-Infective Agents,
pubmed-meshheading:12200946-Cell Line,
pubmed-meshheading:12200946-Humans,
pubmed-meshheading:12200946-Membrane Potentials,
pubmed-meshheading:12200946-Menthol,
pubmed-meshheading:12200946-Muscle, Skeletal,
pubmed-meshheading:12200946-Rats,
pubmed-meshheading:12200946-Sodium Channels,
pubmed-meshheading:12200946-Thymol
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pubmed:year |
2002
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pubmed:articleTitle |
Voltage-dependent block of neuronal and skeletal muscle sodium channels by thymol and menthol.
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pubmed:affiliation |
Hannover Medical School, Department of Anaesthesiology, D-30623 Hannover, Germany. Haeseler.Gertrud@MH-Hannover.de
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pubmed:publicationType |
Journal Article
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