Linked Life Data

12200626

Source:http://linkedlifedata.com/resource/pubmed/id/12200626

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
2002-8-29
pubmed:abstractText
Immunocytochemistry and microdensitometry applied under standardised conditions were used to evaluate neuronal nitric oxide synthase (NOS1) antigen in segmental motor neurones (MN) of six subjects without neurological disease, nine subjects with sporadic motor neurone disease (MND) and five with neurological disease unrelated to MND. No significant segmental differences in levels of NOS1 immunoreactivity occurred between the two control groups, and differences between cervical, thoracic and lumbar MN of the three subject groups were not significant. However, MND patients showed a significantly reduced level of NOS1 immunoreactivity in the Onuf's nucleus (ON); this is discussed in relation to neuroprotection and the relative sparing of ON in MND.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
0001-6322
pubmed:author
pubmed:issnType
Print
pubmed:volume
104
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
391-7
pubmed:dateRevised
2007-11-9
pubmed:meshHeading
pubmed:year
2002
pubmed:articleTitle
Reduced neuronal nitric oxide synthase (NOS1) antigen in sacral motor neurones in motor neurone disease.
pubmed:affiliation
Barts and The London, Queen Mary's School of Medicine and Dentistry, Whitechapel, London E1 BB, UK.
pubmed:publicationType
Journal Article, Comparative Study, Research Support, Non-U.S. Gov't