Linked Life Data

12199550

Source:http://linkedlifedata.com/resource/pubmed/id/12199550

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
2002-8-29
pubmed:abstractText
Exposure to extremely low frequency electric and magnetic fields will induce electric fields and currents within the body, but these are almost always much lower than those that can stimulate peripheral nerve tissue. Guidance on exposure to such fields has been published by NRPB and ICNIRP, which is based on the avoidance of acute effects in the central nervous system. Weak electric field effects, below action potential thresholds, have been demonstrated in vitro in brain slice preparations; thresholds can be estimated to be above about 1 mV mm(-1) (around 100 mA m(-2), taking a brain tissue conductivity of around 0.1 S m(-1)), depending on stimulus conditions. Some studies suggest possible effects at lower induced field strengths. The intact nervous system might be expected to be more sensitive to induced electric fields and currents than in vitro preparations, due to a higher level of spontaneous activity and a greater number of interacting neurons. There is good evidence that electrically excitable cells in the retina can be affected in vivo by induced currents as low as 10 mA m(-2). It has been suggested that induced current densities above 10 mA m(-2) may have effects on other central nervous system functions but few studies have been carried out. Further research in experimental animals using both in vitro and in vivo approaches is needed to clarify this issue.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
0017-9078
pubmed:author
pubmed:issnType
Print
pubmed:volume
83
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
366-75
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed:year
2002
pubmed:articleTitle
Weak electric field interactions in the central nervous system.
pubmed:affiliation
National Radiological Protection Board, Chilton, Didcot, Oxfordshire. richard.saunders@nrpb.org
pubmed:publicationType
Journal Article