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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
3
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pubmed:dateCreated |
2002-8-28
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pubmed:abstractText |
High mobility group (HMG) B1 is a nonhistone nuclear protein that was recently identified as a late-acting mediator of lipopolysaccharide-induced lethality in mice. The proinflammatory actions of HMGB1 have been localized to a region of the molecule called the B box.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Antibodies,
http://linkedlifedata.com/resource/pubmed/chemical/HMGB1 Protein,
http://linkedlifedata.com/resource/pubmed/chemical/NF-kappa B,
http://linkedlifedata.com/resource/pubmed/chemical/NOS2 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Nitric Oxide,
http://linkedlifedata.com/resource/pubmed/chemical/Nitric Oxide Synthase,
http://linkedlifedata.com/resource/pubmed/chemical/Nitric Oxide Synthase Type II,
http://linkedlifedata.com/resource/pubmed/chemical/Nos2 protein, mouse,
http://linkedlifedata.com/resource/pubmed/chemical/Peroxynitrous Acid,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, Immunologic,
http://linkedlifedata.com/resource/pubmed/chemical/advanced glycosylation end-product...
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pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
0016-5085
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
123
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
790-802
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pubmed:dateRevised |
2011-10-27
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pubmed:meshHeading |
pubmed-meshheading:12198705-Animals,
pubmed-meshheading:12198705-Antibodies,
pubmed-meshheading:12198705-Caco-2 Cells,
pubmed-meshheading:12198705-Cell Death,
pubmed-meshheading:12198705-Cell Nucleus,
pubmed-meshheading:12198705-Enterocytes,
pubmed-meshheading:12198705-HMGB1 Protein,
pubmed-meshheading:12198705-Humans,
pubmed-meshheading:12198705-Ileum,
pubmed-meshheading:12198705-Intestinal Mucosa,
pubmed-meshheading:12198705-Male,
pubmed-meshheading:12198705-Mice,
pubmed-meshheading:12198705-Mice, Inbred C57BL,
pubmed-meshheading:12198705-NF-kappa B,
pubmed-meshheading:12198705-Nitric Oxide,
pubmed-meshheading:12198705-Nitric Oxide Synthase,
pubmed-meshheading:12198705-Nitric Oxide Synthase Type II,
pubmed-meshheading:12198705-Permeability,
pubmed-meshheading:12198705-Peroxynitrous Acid,
pubmed-meshheading:12198705-Receptors, Immunologic
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pubmed:year |
2002
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pubmed:articleTitle |
HMGB1 B box increases the permeability of Caco-2 enterocytic monolayers and impairs intestinal barrier function in mice.
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pubmed:affiliation |
Department of Critical Care Medicine, University of Pittsburgh Medical School, Pittsburgh, Pennsylvania 15261, USA.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
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