|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
9
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|
pubmed:dateCreated |
2002-8-28
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|
pubmed:abstractText |
Irinotecan and raltitrexed are active agents in metastatic colorectal cancer. Preclinical findings suggest a remarkable synergistic activity between the two drugs and the feasibility of this association has been shown in a recent phase I study. The aim of our phase II trial was to assess the efficacy and tolerability of the combination of irinotecan and raltitrexed in patients with metastatic colorectal cancer untreated with chemotherapy.
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pubmed:language |
eng
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|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
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pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Sep
|
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pubmed:issn |
0923-7534
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pubmed:author |
|
|
pubmed:issnType |
Print
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pubmed:volume |
13
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pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
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pubmed:pagination |
1424-9
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:12196368-Adult,
pubmed-meshheading:12196368-Aged,
pubmed-meshheading:12196368-Antineoplastic Combined Chemotherapy Protocols,
pubmed-meshheading:12196368-Camptothecin,
pubmed-meshheading:12196368-Colorectal Neoplasms,
pubmed-meshheading:12196368-Confidence Intervals,
pubmed-meshheading:12196368-Dose-Response Relationship, Drug,
pubmed-meshheading:12196368-Drug Administration Schedule,
pubmed-meshheading:12196368-Female,
pubmed-meshheading:12196368-Humans,
pubmed-meshheading:12196368-Male,
pubmed-meshheading:12196368-Middle Aged,
pubmed-meshheading:12196368-Neoplasm Staging,
pubmed-meshheading:12196368-Palliative Care,
pubmed-meshheading:12196368-Probability,
pubmed-meshheading:12196368-Prognosis,
pubmed-meshheading:12196368-Quinazolines,
pubmed-meshheading:12196368-Severity of Illness Index,
pubmed-meshheading:12196368-Survival Analysis,
pubmed-meshheading:12196368-Thiophenes,
pubmed-meshheading:12196368-Treatment Outcome
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|
pubmed:year |
2002
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|
pubmed:articleTitle |
Irinotecan and raltitrexed: an active combination in advanced colorectal cancer.
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|
pubmed:affiliation |
Medical Oncology and Haematology Department, Istituto Clinico Humanitas, Milan, Italy.
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pubmed:publicationType |
Journal Article,
Clinical Trial,
Comparative Study,
Clinical Trial, Phase II
|
