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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
46 Suppl
|
| pubmed:dateCreated |
1976-5-25
|
| pubmed:abstractText |
The dialysance of acebutolol, in vitro, has been found to be equal to 87 ml/mn for a blood flow of 200 ml/mn through an artificial kidney; at the same flow rate, that of urea is 136 ml/mn. In subjects with normal renal function, half-life of acebutolol in plasma, after oral administration, is 4.4 +/- 0.6 h; in haemodialysed patients with renal failure, it is very increased; during haemodialysis, it is near normal (mean: 5.9 h in 4 subjects). Authors discuss the meaning of acebutolol dialysance, in vivo, considering a possible protein binding of this drug.
|
| pubmed:language |
fre
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Dec
|
| pubmed:issn |
0301-1518
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:day |
31
|
| pubmed:volume |
4
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
3228-33
|
| pubmed:dateRevised |
2010-11-18
|
| pubmed:meshHeading |
pubmed-meshheading:1219629-Acebutolol,
pubmed-meshheading:1219629-Acute Kidney Injury,
pubmed-meshheading:1219629-Half-Life,
pubmed-meshheading:1219629-Humans,
pubmed-meshheading:1219629-Hypertension,
pubmed-meshheading:1219629-Kidney,
pubmed-meshheading:1219629-Metabolic Clearance Rate,
pubmed-meshheading:1219629-Renal Dialysis
|
| pubmed:year |
1975
|
| pubmed:articleTitle |
[Study of acebutolol dialysis and pharmacokinetic data in patients with renal insufficiency undergoing hemodialysis].
|
| pubmed:publicationType |
Journal Article,
In Vitro,
English Abstract
|