Linked Life Data

12185328

Source:http://linkedlifedata.com/resource/pubmed/id/12185328

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
2002-8-19
pubmed:abstractText
Many randomized clinical trials have been performed to address the effectiveness of postmastectomy radiation therapy (PMRT) to regional lymph nodes with or without chest wall irradiation. Although these studies have confirmed the usefulness of RT to reduce loco-regional recurrence, the benefit of postoperative RT for survival remains controversial. Recent prospective trials of PMRT in combination with systemic chemotherapy clearly demonstrated the benefit of this combined adjuvant therapy for both locoregional recurrence and survival outcomes. Based upon this new evidence, guidelines and recommendations for PMRT in the management of breast cancer have been proposed by the American Society of Clinical Oncology and by the International Consensus Panel at the International Conference on Adjuvant Therapy of Primary Breast Cancer in St. Gallen. PMRT is recognized as a standard adjuvant treatment for patients with more than 4 positive axillary nodes in these guidelines and recommendations. This re-appraisal of PMRT has not attracted much attention in Japan so far. Clinical studies are needed to determine how to best incorporate PMRT in the multimodal treatment of node-positive breast cancer.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:issn
1340-6868
pubmed:author
pubmed:issnType
Print
pubmed:volume
9
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
190-5
pubmed:dateRevised
2007-11-15
pubmed:meshHeading
pubmed:year
2002
pubmed:articleTitle
Adjuvant radiation therapy following mastectomy for breast cancer.
pubmed:affiliation
Department of Therapeutic Radiology and Oncology, Kyoto University Graduate School of Medicine, 54 Kawahara-cho, Shogoin, Sakyo-ku, Kyoto 606-8507, Japan.
pubmed:publicationType
Journal Article, Review