Source:http://linkedlifedata.com/resource/pubmed/id/12183624
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5584
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pubmed:dateCreated |
2002-8-16
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pubmed:abstractText |
Ambient optical detection of labeled molecules is limited for fluorescent dyes by photobleaching and for semiconducting nanoparticles by "blinking" effects. Because nanometer-sized metal particles do not optically bleach, they may be useful optical labels if suitable detection signals can be found. We demonstrate far-field optical detection of gold colloids down to diameters of 2.5 nanometers with a photothermal method that combines high-frequency modulation and polarization interference contrast. The photothermal image is immune to the effects of scattering background, which limits particle imaging through Rayleigh scattering to diameters larger than 40 nanometers.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:status |
PubMed-not-MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
1095-9203
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pubmed:author | |
pubmed:issnType |
Electronic
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pubmed:day |
16
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pubmed:volume |
297
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1160-3
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pubmed:dateRevised |
2007-3-19
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pubmed:year |
2002
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pubmed:articleTitle |
Photothermal imaging of nanometer-sized metal particles among scatterers.
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pubmed:affiliation |
Physique Moléculaire Optique et Hertzienne, CNRS et Université Bordeaux I, 351 Cours de la Libération, 33405 Talence Cedex, France.
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pubmed:publicationType |
Journal Article
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